课题基金 / 基金详情

PRECLINICAL TOXICOLOGY & PHARMACOLOGY OF DRUGS DEVELOPED

PRECLINICAL TOXICOLOGY & PHARMACOLOGY OF DRUGS DEVELOPED
临床前毒理学
批准号：
6355503
负责人：
BARRY S LEVINE
金额：
$8.0万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-01-15 至 2003-01-14
来源：
https://reporter.nih.gov/project-details/6355503
关键词：
Primates antiAIDS agent antineoplastics dogs dosage drug screening /evaluation laboratory mouse laboratory rat mass spectrometry microorganism disease chemotherapy neoplasm /cancer chemotherapy neoplasm /cancer pharmacology nonhuman therapy evaluation nuclear magnetic resonance spectroscopy pharmacokinetics pharmacology toxicology

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中文摘要
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英文摘要
The objective of this contract is to acquire pharmacologic and toxicologic data on new drugs for the treatment of Cancer and the Acquired Immunodeficiency Syndrome (AIDS) and AIDS-related illnesses. The data will be included in an Investigational New Drug (IND) application to the FDA which is required prior to the initiation of human clinical trials. Level A contract is 46,875 hours over 5 years. Level B contract is 93,750 hours over 5 years. This contract will be awarded at Level A because the laboratory has the capability, expertise and experience to do the amount of work required.
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会议论文
FOURTEEN DAY ORAL RANGEFINDING STUDIES AND TWENTY-EIGHT
TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS TO
FOURTEEN DAY ORAL RANGEFINDING STUDY IN RATS AND DOGS AN
TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS TO
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