A novel therapy for the prevention and treatment of familial hypertrophic cardiomyopathy

预防和治疗家族性肥厚型心肌病的新疗法

• 批准号: nhmrc : GNT1103782
• 负责人: A/Pr Livia Hool
• 金额: $ 83.6万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-therapy-prevention-hypertrophic-cardiomyopathy/1346304
• 关键词: novel; therapy; prevention; treatment; familial

Familial hypertrophic cardiomyopathy is a genetic disorder that leads to enlargement of the heart, cardiac failure and sudden death. No treatment exists that can reverse or prevent the cardiomyopathy. In this proposal we will determine whether a peptide (Patent WO2013/113060) targeting a calcium channel can prevent or reverse the cardiomyopathy as a novel treatment for the disease.

家族性肥厚型心肌病是一种遗传性疾病，可导致心脏增大、心力衰竭和猝死。没有治疗方法可以逆转或预防心肌病。在该提议中，我们将确定靶向钙通道的肽（专利WO 2013/113060）是否可以预防或逆转心肌病作为该疾病的新治疗。