TRAINING PROGRAM IN FREE RADICAL AND RADIATION BIOLOGY

爱荷华大学的自由基和辐射生物学培训计划以辐射研究实验室为基础，旨在为学员在辐射和自由基生物学的职业生涯做准备的教育中的五个关键目标：1)传授辐射生物学、自由基生物学和分子肿瘤学的基本知识，并在一个或多个明确的领域深入精通；2)为学员提供精通辐射生物学、自由基生物学和分子肿瘤学学科的机会；3)为受训人员安排研究经验，包括制定研究建议、执行研究项目以及在同行评议的出版物中对这些结果进行评估。4)为学员提供学习必要的领域知识和技能的经验，以便与临床和基础科学系的教师进行合作研究；以及5)鼓励学员在“真实世界”环境中实施创新方法，以测试关于放射生物学和自由基现象的机制和后果的明确假设。博士项目始于1960年，现已发展到平均招收14名学生。到目前为止，已有90名毕业生，其中47人获得了学术放射生物学研究的职位，14人在学术医学或牙科执业，19人在工业工作，其余的在各种岗位上。自1991年8月以来，已有30名学生注册了辐射生物学学位课程。通过这项申请，我们提议在四年内每年支持四名博士生。我们拥有一大批国际公认的教职员工，他们持续参与国家认可的放射生物学和自由基研究项目、计划项目、个人研究奖项，爱荷华大学癌症中心教育为我们的学员提供一对一的指导，从事与癌症相关的国家认可的研究项目，外加该系提供的正式课程工作和爱荷华大学的其他优秀资源。教师、研究员和学生组成了一个关键群体，为研讨会、期刊俱乐部和非正式讨论提供了一个具有挑衅性的环境。我们在爱荷华大学辐射研究实验室的资源为学员提供了接触最先进的放射生物学、自由基和癌症研究的第一手机会和培训。

The University of Iowa Training Program in Free Radical and Radiation Biology, based in the Radiation Research Laboratory, is oriented around five key goals for education in preparation of trainees for a career in radiation and free radical biology: 1) To impart a fundamental understanding of the subject matter of radiation biology, free radical biology, and molecular oncology and an in-depth proficiency in one or more defined areas: 2) To provide trainees with the opportunity to achieve proficiency in radiation biology, free radical biology, and molecular oncology disciplines; 3) To structure research experience for trainees that includes the development of a research proposal, execution of a research project, and evaluation of these results in peer-reviewed publications. 4) To offer trainees experience in learning the necessary domain knowledge and skills to do collaborative research with faculty in clinical and basic science departments; and 5) To encourage trainees to implement innovative approaches in a "real world" environment to test explicit hypotheses about the mechanisms and consequences of radiobiologic and free radical phenomena. The doctoral program began in 1960 and has grown to an average enrollment of 14 students. There have been 90 graduates thus far, 47 of whom have obtained positions in academic radiobiology research, 14 are practicing academic medicine or dentistry, 19 are working in industry, and the remainder are in a variety of positions. Since August 1991, 30 students have enrolled in radiation biology degree programs. With this application, we are proposing to support four doctoral candidates each year for four years. We have a large internationally recognized faculty with consistent involvement in nationally recognized radiobiology and free radical research projects, program projects, individual research awards, and The University of Iowa Cancer Center Education for our trainees involves one-on-one mentoring by faculty members, working on cancer-related nationally recognized research projects, plus formal course work offered by the department and the other excellent resources at The University of Iowa. The faculty, fellows, and students form a critical mass for providing a provocative environment for seminars, journal clubs, and informal discussion. Our resources at The University of Iowa Radiation Research Laboratory offer trainees opportunities to obtain first-hand exposure to and training on state-of-the-art radiobiological, free radical, and cancer research.