Training Program in Free Radical and Radiation Biology

自由基和放射生物学培训计划

• 批准号: 7197193
• 负责人: LARRY OBERLEY
• 金额: $ 3.14万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7197193
• 关键词: Training; Program; Free; Radical; Radiation

DESCRIPTION (provided by applicant): The University of Iowa Training Program in Free Radical and Radiation Biology is oriented around six key goals for education in preparation of trainees for a career in free radical and radiation biology: 1) To impart a fundamental understanding of the subject matter of radiation biology, free radical biology, and cancer biology; 2) To provide trainees with the opportunity to achieve proficiency in the radiation biology, free radical biology, and molecular oncology disciplines leading to successful careers in cancer research; 3) To structure research experience for trainees that includes the development of a research proposal, execution of a research project, and evaluation of these results for submission in peer-reviewed publications; 4) To offer trainees experience in learning the necessary knowledge and skills to do collaborative research with faculty in clinical and basic science departments; 5) To provide trainees with critical knowledge of the structure of science and essential skills in both oral and written scientific communication; and 6) To encourage trainees to implement innovative approaches in a "real world" environment to test explicit hypotheses about the mechanisms and consequences of radiobiological and free radical phenomena. With this application, we are proposing to continue to support three predoctoral trainees per year and also to phase in the additional support of postdoctoral trainees. We propose to support one postdoctoral trainee in the first year, two in the second, and three in years 3-5. We have an internationally recognized faculty with consistent involvement in nationally recognized radiobiology and free radical research projects, program projects, individual research awards, and The University of Iowa Cancer Center. We propose to have 10 mentors in the Training Program, 4 from the Department of Radiation Oncology and one each from the Departments of Internal Medicine, Pathology, Surgery, Anatomy and Cell Biology, Exercise Science, and Chemistry. Education for our trainees involves one-on-one mentoring by faculty members, working on cancer related nationally recognized research projects, presenting work and receiving feedback at national meetings, plus formal course work offered by the department and the other excellent resources at The University of Iowa. Formal coursework includes classes in radiation, free radical, and cancer biology. The faculty, fellows, and students form a critical mass for providing a provocative environment for seminars, journal clubs, and informal discussion. Research being pursued goes from the bench top to the clinic. Communication, both verbal and written, is stressed in the Training Program, so that the science that is done can be communicated to other scientists. We believe this Training Program has all the ingredients necessary to produce the needed high quality scientists in free radical and radiation biology who will work in cancer research.

描述(由申请者提供)：爱荷华大学自由基和辐射生物学培训计划围绕六个关键教育目标，为学员在自由基和辐射生物学领域的职业生涯做准备： 1)对辐射生物学、自由基生物学和癌症生物学的主题有一个基本的了解； 2)为学员提供精通辐射生物学、自由基生物学和分子肿瘤学学科的机会，这些学科有助于在癌症研究领域取得成功； 3)为受训人员安排研究经验，包括制定研究建议、执行研究项目和评估这些结果，以便在同行评议的出版物中提交； 4)为学员提供学习所需知识和技能的经验，以便与临床和基础科学系的教员进行合作研究； 5)向学员提供有关科学结构的批判性知识，以及口头和书面科学交流的基本技能；以及 6)鼓励受训者在“真实世界”环境中实施创新方法，以测试关于放射生物学和自由基现象的机制和后果的明确假设。 通过这项申请，我们建议继续每年支持三名博士后实习生，并逐步增加对博士后实习生的支持。我们建议在第一年支持一名博士后实习生，在第二年支持两名，在第三到第五年支持三名博士后实习生。我们拥有一支国际公认的教师队伍，持续参与国家认可的放射生物学和自由基研究项目、计划项目、个人研究奖项以及爱荷华大学癌症中心。我们建议在培训计划中有10名导师，4名来自放射肿瘤科，1名来自内科、病理学、外科、解剖学和细胞生物学、运动科学和化学系。我们为学员提供的教育包括由教员提供一对一的指导，从事与癌症相关的全国公认的研究项目，在全国会议上展示工作并收到反馈，以及系里提供的正式课程工作和爱荷华大学的其他优秀资源。正规课程包括辐射、自由基和癌症生物学的课程。教师、研究员和学生组成了一个关键群体，为研讨会、期刊俱乐部和非正式讨论提供了一个具有挑衅性的环境。正在进行的研究从工作台到诊所。培训计划强调口头和书面的交流，以便将所做的科学交流给其他科学家。我们相信，这一培训计划具备培养出从事癌症研究的自由基和辐射生物学方面的高素质科学家所需的所有必要成分。