TEMPORAL CODES AND CORTICOCORTICAL COMMUNICATION

时间编码和皮质通讯

基本信息

  • 批准号:
    6393564
  • 负责人:
  • 金额:
    $ 19.31万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1998
  • 资助国家:
    美国
  • 起止时间:
    1998-07-01 至 2003-04-30
  • 项目状态:
    已结题

项目摘要

The broad aim of the proposed studies is to define the role of temporal codes in corticocortical information processing. Current models of coincidence detection and temporal integration of average firing rates are directly examined with an experimental approach. Pattern recognition and directing attention are chosen as related cortical functions which are likely to select for different processing strategies. Pattern recognition which requires fast, parallel and exhaustive, binding of multiple features within and across many scales is likely to depend on the fast timing schemes identified in coincidence detection models. Directing attention, on the other hand, reflects the deploying of a narrow information channel. This process is likely to depend on slower, serial search schemes that are well supported by rate coding strategies that mark more highly active neural sub-populations. Specific experimental methods are proposed to test the utilization of these strategies by neurons in the awake animal engaged in simple but well-defined behavioral tasks. The significance of these studies is to build our understanding of the nature of temporal processing in cortical dynamics. Knowledge of the mechanisms of temporal integration is the next crucial step in approaching the varied problems of brain injury. Increasing evidence points to the disruption of temporal processing as a fundamental mechanism underlying developmental and acquired cognitive disabilities. Morever, the first hints of therapeutic approaches based on models of temporal processing suggest that further detailed knowledge of the timing of information flow in the cortex will assist the efforts to improve the lives of patients with dyslexia, head trauma and stroke. Ultimately, the brain is organized with parallel and vertical subcortical connections (limbic, striatal, thalamocortical) as well as the corticocortical connections emphasized here. The studies proposed will seek to frame the understanding of corticocortical interactions in a context that will support further studies of thalamocortical integration. Building out from this framework will enlarge the possible scope of significance for the treatment of brain disorders.
拟议研究的主要目的是确定时间的作用

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Keith P. Purpura其他文献

Système et procédés pour l'activation multi-site du thalamus
丘脑多部位激活系统及程序
  • DOI:
  • 发表时间:
    2014
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Nicholas D. Schiff;Keith P. Purpura;Jonathan L. Baker;Jae
  • 通讯作者:
    Jae

Keith P. Purpura的其他文献

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{{ truncateString('Keith P. Purpura', 18)}}的其他基金

Role of fixational eye movements and saccades in processing spatial information in V1-V2-V4 networks
注视眼运动和扫视在处理 V1-V2-V4 网络空间信息中的作用
  • 批准号:
    10503661
  • 财政年份:
    2022
  • 资助金额:
    $ 19.31万
  • 项目类别:
Role of fixational eye movements and saccades in processing spatial information in V1-V2-V4 networks
注视眼运动和扫视在处理 V1-V2-V4 网络空间信息中的作用
  • 批准号:
    10685318
  • 财政年份:
    2022
  • 资助金额:
    $ 19.31万
  • 项目类别:
Processing of spatial information in V1 through fixational eye movements
通过注视眼球运动处理 V1 中的空间信息
  • 批准号:
    9374079
  • 财政年份:
    2017
  • 资助金额:
    $ 19.31万
  • 项目类别:
TEMPORAL CODES AND CORTICOCORTICAL COMMUNICATION
时间编码和皮质通讯
  • 批准号:
    6188116
  • 财政年份:
    1998
  • 资助金额:
    $ 19.31万
  • 项目类别:
TEMPORAL CODES AND CORTICOCORTICAL COMMUNICATION
时间编码和皮质通讯
  • 批准号:
    2892301
  • 财政年份:
    1998
  • 资助金额:
    $ 19.31万
  • 项目类别:
TEMPORAL CODES AND CORTICOCORTICAL COMMUNICATION
时间编码和皮质通讯
  • 批准号:
    2635811
  • 财政年份:
    1998
  • 资助金额:
    $ 19.31万
  • 项目类别:
CORTICOCORTICAL INTERACTIONS IN VISION
视觉中的皮质相互作用
  • 批准号:
    2460452
  • 财政年份:
    1993
  • 资助金额:
    $ 19.31万
  • 项目类别:
CORTICOCORTICAL INTERACTIONS IN VISION
视觉中的皮质相互作用
  • 批准号:
    2259736
  • 财政年份:
    1993
  • 资助金额:
    $ 19.31万
  • 项目类别:
CORTICOCORTICAL INTERACTIONS IN VISION
视觉中的皮质相互作用
  • 批准号:
    3075236
  • 财政年份:
    1993
  • 资助金额:
    $ 19.31万
  • 项目类别:
CORTICOCORTICAL INTERACTIONS IN VISION
视觉中的皮质相互作用
  • 批准号:
    2259737
  • 财政年份:
    1993
  • 资助金额:
    $ 19.31万
  • 项目类别:

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