Fourth International Conference--Varicella Zoster Virus

说明（由申请人提供）：正在申请资金，以支持 第四届水痘-带状疱疹病毒（VZV）国际会议。 先前 会议于1992年在马里兰州贝塞斯达举行（与NIH合作）， 1994年在法国巴黎，1997年在佛罗里达的棕榈海滩。 的目的 这些会议将为研究人员、学者和 参与VZV研究的临床医生有一个科学交流的场所。 会议计划于2001年3月3日至5日在加利福尼亚州拉霍亚举行。 VZV是引起水痘和带状疱疹的病原体， 两者都是人类的重要病原体。 Zoster尤其是 50岁以上的人的医疗问题， 表现为皮疹，但也可能伴有剧烈疼痛， 可能会持续数月至数年后，原来的疾病，这种情况称为 带状疱疹后神经痛（PHN）。 2001年会议将讨论的主题包括 第一天，因为会议开始在一个周末，当临床医生更多 可能是可用的。 一次会议将专门讨论水痘和 除了Zoster。 第一次正式会议将专门讨论治疗问题， 预防水痘和带状疱疹，重点是 疫苗和抗病毒药物。 将有一个关于PCR方法的特别讲习班 Perkin-Elmer 在第二天，VZV研究的基本方面将是 讨论并将包括病毒复制，基因调控， 病毒-细胞蛋白相互作用、动物模型、潜伏期和宿主反应。 还将有一系列的“最先进的”讲座，由专家在 在过去的会议上没有发言的人。这些会谈将包括 会议上提出的重要数据摘要，并将努力 整合了关于水痘和带状疱疹的新旧概念。

Description (provided by applicant): Funds are being requested to support the Fourth International Conference on the Varicella-Zoster Virus (VZV). Previous conferences were held in Bethesda, MD, in 1992 (in conjunction with NIH), in Paris, France in 1994, and in Palm Beach, Florida in 1997. The purpose of these meetings is to provide a forum for researchers, academicians, and clinicians involved in VZV research to have a venue for scientific exchange. The meeting is planned to occur March 3-5, 2001 in LaJolla, CA. VZV is the agent that causes varicella (chickenpox) and zoster (shingles), both of which are important pathogens for humans. Zoster is particularly a medical problem for individuals over the age of 50 years in whom it can only be manifested as a skin rash but also may be associated with severe pain that may persist for months to years after the original illness, a condition termed post herpetic neuralgia (PHN). Topics to be discussed in the 2001 meeting will include clinical topics on the first day because the conference begins on a weekend when clinicians are more likely to be available. One session will be devoted to Varicella and the other to Zoster. The first formal sessions will be devoted to treatment and prevention of varicella and zoster, with an emphasis on new developments in vaccines and antiviral drugs. There will be a special workshop on PCR methods by Perkin-Elmer. On the second day, basic aspects of VZV research will be discussed and will include the topics of virus replication, gene regulation, virus-cell protein interaction, animal models, latency, and host responses. There will also be a series of "State of the Art" lectures by experts in the field who have not presented at past meetings. These talks will include a summary of important data presented at the meeting and will attempt to integrate old and new concepts concerning varicella and zoster.