CELL HARVESTER & MULTILABEL COUNTER

细胞采集器

• 批准号: 6053095
• 负责人: Dennis L. Kasper
• 金额: $ 13.31万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6053095
• 关键词: biomedical equipment purchase; cell sorting

The development of automated equipment for the analysis of cellular proliferation, enzyme function, apoptosis, cell-cell interactions, and receptor-ligand studies has greatly facilitated research in these areas. The Wallac Microbetaplate Trilux harvester and Victor multilabel counter are components of an integrated system that measures radioactivity, chemiluminescence, fluorescence, and photometry. This equipment allows for analysis of a large number of samples in an automated fashion and can be used for quantitative measurement of labeled molecules. Its versatility should greatly enhance the progress of MH supported research. Due to the major cost involved in its purchase, the instrument must be considered for shared-use. This proposal outlines the Research Plans of six major users and requests funding for its purchase. The NIH funded research outlined encompass a broad range of technologies that will all greatly benefit from use of this equipment. The six major users are all members of the Channing Laboratory and have a strong history of collaboration and scientific interaction. The shared use of this instrument will exemplify the model of the Channing Laboratory in which resources are pooled to strengthen the overall research effort of its members. The use of the proposed instrument should serve to fortify this effort. In summary, this proposal requests funds for the purchase of a Wallac Microbetaplate Trilux harvester and Victor multilabel counter that will be shared by six major users. A major commitment has been made by these users, including the Director of the Channing Laboratory, to provide the financial support required to maintain and operate the instrument. The availability of the instrument will greatly accelerate the MH funded research outlined.

用于分析细胞增殖、酶功能、细胞凋亡、细胞间相互作用和受体-配体研究的自动化设备的开发极大地促进了这些领域的研究。Wallac Microbetaplate Trilux采集器和维克托多标记计数器是测量放射性、化学发光、荧光和光度测定的集成系统的组件。该设备允许以自动化方式分析大量样品，并可用于标记分子的定量测量。它的多功能性应大大提高MH支持的研究的进展。由于其购买涉及的主要成本，该工具必须考虑共享使用。该提案概述了六个主要用户的研究计划，并要求为其购买提供资金。NIH资助的研究概述了广泛的技术，这些技术都将从使用这种设备中受益匪浅。六个主要用户都是钱宁实验室的成员，有着很强的合作和科学互动的历史。共享使用这一工具将使钱宁实验室的模式更加完善，在这种模式中，资源被集中起来，以加强其成员的整体研究工作。拟议文书的使用应有助于加强这一努力。总之，本提案要求提供资金，用于购买Wallac Microbetaplate Trilux采集器和维克托多标签计数器，由六个主要用户共用。包括钱宁实验室主任在内的这些用户已作出重大承诺，将提供维护和操作该仪器所需的财政支助。该仪器的可用性将大大加快MH资助的研究概述。

项目成果

Maintaining patency of tunneled hemodialysis catheters--efficacy of aspirin compared to warfarin.

保持隧道式血液透析导管的通畅——阿司匹林与华法林的疗效比较。

• DOI: 10.1080/00365590310008938
• 发表时间: 2003
• 期刊: Scandinavian journal of urology and nephrology.
• 作者: Obialo,ChamberlainI;Conner,AnitaC;Lebon,LindaF
• 通讯作者: Lebon,LindaF