RESEARCH TRAINING IN DEMENTIAS OF AGING

这项申请要求继续为我们非常成功的 老年痴呆症研究训练计划。这个节目， 始于1987年，教授博士后内科医生和心理学家如何 对重大公共卫生疾病进行高质量的研究 在老年人中的重要意义。大部分的研究性培训是 约翰·霍普金斯大学目前资助的项目背景 医学。这些措施包括临床和基于人群的调查， 纵向跟踪研究、基于实验室的病例对照研究和 阿尔茨海默病、亨廷顿病、唐氏症的临床试验 神志不清综合症、精神错乱和其他认知障碍综合症。研究 环境包括社区、综合医院和疗养院， 添加到实验室。临床上的大量项目 神经科学目前可供研究员使用，特别强调 关于：仪器和测量发展；之间的相关性 临床/功能指标和脑部异常 神经成像方法；遗传知识和方法学的应用 痴呆症的问题。研究员将获得两年的 研究指导和指导经验，一个完整的教学计划，以及 有神经精神科诊所的经验。该培训的往届毕业生 计划成功地进入了医院和以医学院为基础的医院 作为临床研究人员的职业。

This application requests continued funding for our highly successful program of Research Training in the Dementias of Aging. This program, which began in 1987, teaches postdoctoral physicians and psychologists how to conduct high quality research on disorders of great public health significance among the elderly. Most of the research training is the context of currently-funded projects at the Johns Hopkins School of Medicine. These include clinical and population-based surveys, longitudinal follow-up studies, laboratory-based case-control studies and clinical trials in Alzheimer's disease, Huntington's disease, Down's syndrome, delirium, and other syndromes of cognitive impairment. Research settings include the community, general hospital, and the nursing home, in addition to the laboratory. A large number of projects in the clinical neurosciences are currently available to fellows, with particular emphases on: instrument and measurement development; correlations between clinical/functional indicators and brain abnormalities revealed by neuroimaging methods; and application of genetic knowledge and methodology to the problems of dementing illnesses. Fellows receive two years of research tutelage and supervised experience, a full didactic program, and experience in the neuropsychiatry clinics. Past graduates of this training program have gone on to successful hospital and medical-school-based careers as clinical investigators.