Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)

阿尔茨海默病及相关痴呆症转化研究培训 (TRIAD)

基本信息

  • 批准号:
    10212210
  • 负责人:
  • 金额:
    $ 49.89万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-09-15 至 2023-02-28
  • 项目状态:
    已结题

项目摘要

7. PROJECT SUMMARY/ABSTRACT This is an application for a T32 training grant titled “Training in Translational Research in Alzheimer's Disease and Related Dementias (TRIAD)” to support 4 predoctoral and 4 postdoctoral fellows. The overall goal of the proposed program is to provide cross-disciplinary training from bench to bedside, to produce a new translational workforce that is critically needed to develop and advance effective treatments for Alzheimer's disease and related dementias. Trainees will receive rigorous and innovative translational research education and training through a 3-cluster multidisciplinary and integrative mentoring program that spans the discovery continuum from molecular/biochemical methods, preclinical translational approaches and clinical research. The thematic focus is on risk factors for Alzheimer's disease and related dementias; these risk factors include cerebrovascular disease, neuroinflammation, Down syndrome, and traumatic brain injury. The training program has 18 faculty mentors with established and extensive interactions and collaborations, and successful track records in training. The faculty mentors encompass diverse areas of expertise from cell & molecular biology, genetics, and data science, through preclinical model systems, therapeutic development, neuroimaging, neuropathology, clinical trials, and longitudinal clinical studies. The majority (13) of these mentors are housed within the University of Kentucky Sanders Brown Center on Aging, which includes a long-standing NIA-funded Alzheimer's Disease Center. All faculty with primary appointments in a Center also have academic appointments in other basic science or clinical departments at the University of Kentucky. Predoctoral trainees will be recruited from our Integrated Biomedical Sciences graduate program and from the MD/PhD program in the College of Medicine, and postdoctoral trainees through targeted advertisement and recommendations from colleagues and other Alzheimer's Disease Centers. In addition to their individualized research program and career development plan, each group of trainees will participate in a series of educational experiences that include a dedicated AD101 course in Alzheimer's disease and related dementias, seminars describing research and clinic ethics, monthly research and career development seminars, journal clubs, Training the Trainers workshops, and grant writing workshops. Each year trainees will be expected to present their research at the annual Markesbery Symposium on Aging and Dementia. Postdoctoral trainees will be provided with additional training opportunities, including: 1) a short off-site externship at another laboratory that conducts Alzheimer's disease research and 2) presentations at the annual College of Medicine Postdoctoral Poster Session. Quantitative and qualitative metrics for evaluation of trainees and the training program will assure a high-quality and effective training experience. The outcomes of our program are intended to nurture highly innovative, well-trained scholars who are dedicated and passionate about finding new approaches to prevent or slow Alzheimer's disease and related dementias.
7. 项目总结/文摘

项目成果

期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Being in Place: Toward a Situational Perspective on Care.
就位:从情境角度看待护理。
  • DOI:
    10.1093/geront/gnac049
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Rhodus,ElizabethK;Rowles,GrahamD
  • 通讯作者:
    Rowles,GrahamD
Mitochondrial transplantation strategies as potential therapeutics for central nervous system trauma.
  • DOI:
    10.4103/1673-5374.226382
  • 发表时间:
    2018-03
  • 期刊:
  • 影响因子:
    6.1
  • 作者:
    Gollihue JL;Patel SP;Rabchevsky AG
  • 通讯作者:
    Rabchevsky AG
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Michael Paul Murphy其他文献

Michael Paul Murphy的其他文献

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{{ truncateString('Michael Paul Murphy', 18)}}的其他基金

University of Kentucky SuRE Resource Center
肯塔基大学 SuRE 资源中心
  • 批准号:
    10492898
  • 财政年份:
    2022
  • 资助金额:
    $ 49.89万
  • 项目类别:
Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
阿尔茨海默病和相关痴呆症转化研究培训 (TRIAD)
  • 批准号:
    10493734
  • 财政年份:
    2022
  • 资助金额:
    $ 49.89万
  • 项目类别:
University of Kentucky SuRE Resource Center
肯塔基大学 SuRE 资源中心
  • 批准号:
    10888626
  • 财政年份:
    2022
  • 资助金额:
    $ 49.89万
  • 项目类别:
Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
阿尔茨海默病及相关痴呆症转化研究培训 (TRIAD)
  • 批准号:
    10672322
  • 财政年份:
    2022
  • 资助金额:
    $ 49.89万
  • 项目类别:
Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
阿尔茨海默病及相关痴呆症转化研究培训 (TRIAD)
  • 批准号:
    9759743
  • 财政年份:
    2017
  • 资助金额:
    $ 49.89万
  • 项目类别:
Leptin Signaling and Alzheimer's Disease
瘦素信号传导和阿尔茨海默病
  • 批准号:
    8701451
  • 财政年份:
    2014
  • 资助金额:
    $ 49.89万
  • 项目类别:
Leptin Signaling and Alzheimer's Disease
瘦素信号传导和阿尔茨海默病
  • 批准号:
    8919198
  • 财政年份:
    2014
  • 资助金额:
    $ 49.89万
  • 项目类别:
Lead Exposure in a Novel Mouse Model of Neurologic Disease
新型神经系统疾病小鼠模型中的铅暴露
  • 批准号:
    8754322
  • 财政年份:
    2014
  • 资助金额:
    $ 49.89万
  • 项目类别:
Cellular Nucleic Acid Binding Protein (CNBP) in Aging and Disease
细胞核酸结合蛋白 (CNBP) 在衰老和疾病中的作用
  • 批准号:
    7800333
  • 财政年份:
    2007
  • 资助金额:
    $ 49.89万
  • 项目类别:
Cellular Nucleic Acid Binding Protein (CNBP) in Aging and Disease
细胞核酸结合蛋白 (CNBP) 在衰老和疾病中的作用
  • 批准号:
    8040017
  • 财政年份:
    2007
  • 资助金额:
    $ 49.89万
  • 项目类别:
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