PHYS SCI RES TRAINING IN PATHOGENESIS OF VIRAL DISEASES

描述：（改编自应用程序）：病毒性疾病是一种主要的 对儿童和成人的威胁。 迅速崛起， 相对较新的人类病原体如艾滋病毒的传播， 死亡率与持续感染有关， 丙型肝炎以及间歇性和经常无法解释的复发 埃博拉病毒等病原体强调了训练有素的 能够迅速应对此类公共卫生问题的调查人员。 的 这项研究培训补助金的目标是准备医生（M.D.和 医学博士/博士）作为独立调查员的职业， 病毒的发病机制，主要集中在病毒/宿主的相互作用。 十二名教师代表了这一关键培训人员， 计划已被选定为他们在病毒领域的良好记录- 宿主相互作用，它们桥接临床和基础领域的能力， 真正致力于培养未来的医学科学家。 近期 招募和晋升几个人在山。西奈 强调机构承诺发展强大的 补充研究计划，不仅在基础科学部门 而且在临床部门也是如此。 每个调查员都扮演一个 在研究生院以及他或她各自的临床 部门，并已制定了广泛的协作互动，将 为受训人员提供一个重要的和可利用的专门知识网络。 该计划旨在扩大最近重组的培训 成人和儿童传染病奖学金。 这些项目及其 部门最近经历了领导层的变化，任命 联合主任担任各司司长，并着重强调今后的培训 物理科学家 候选人将进入一个研究培训轨道， 他们的第二年研究金，并将成为培训补助金的候选人 第三年（PGY 6）和第四年（PGY 7）。 主要活动 在研究金的第三和第四年， 对个别项目进行调查。 这一经验将得到补充 通过参与多学科博士学位的核心课程，程序 疾病的分子基础，每周杂志俱乐部，每周实验室数据 会议以及司、部和机构的研究会议。 该计划的目标是为学员提供必要的技能 和培训，以有效地竞争赠款奖励作为下一步， 过渡到独立的职业生涯作为传染病医生科学家。

DESCRIPTION: (adapted from the application): Viral diseases are a major threat to the pediatric and the adult populations. The rapid emergence and spread of relatively new human pathogens such as HIV, the increasing morbidity and mortality associates with persistent infection with agents such as Hepatitis C as well as the episodic and often unexplained reemergence of pathogens such as Ebola virus underscore the need for well trained investigators who can respond rapidly to such public health problems. The goal of this research training grant is to prepare physicians (M.D. and M.D./Ph.D.) for careers as independent investigators specifically in the area of viral pathogenesis, with a primary focus on virus/host interactions. The twelve faculty members representing the key training personnel for this program have been selected for their strong track record in the area of virus- host interaction, their ability to bridge clinical and basic arenas, and their genuine commitment to training future physician-scientists. The recent recruitment and promotion of several of thee individuals at Mt. Sinai underscores the institutional commitment to developing strong and complementary research programs, not only within the basic science departments but also within the clinical departments. Each of the investigators plays a major role in the graduate school as well as in his or her respective clinical department and has developed extensive collaborative interactions that will provide the trainees a critical and accessible network of expertise. The program is designed to expand the training in the recently reorganized Adult and Pediatric Infectious Diseases fellowships. These programs and their department have undergone recent changes in leadership, with the appointment of the Co-Directors as Division Heads and a major emphasis on training future physician-scientists. The candidates will enter a research training track in their second year of fellowship and will be candidates for training grant funding for their third (PGY6) and fourth (PGY7) year. The major activity during the third and fourth year of the fellowship will be mentored laboratory investigation on an individual project. This experience will be complemented by participation in the core course of the multidisciplinary Ph.D. program Molecular Basis of Diseases , weekly journal club, weekly laboratory data sessions and divisional, departmental and institutional research conferences. The goal of this program is to provide the trainees with the necessary skills and training to effectively compete for grant awards as the next step in their transition to independent careers as infectious diseases physician-scientists.