STRUCTURE DETERMINATION OF PEPTIDYLGLYCINE HYDROXYLATING MONOOXGENASE

PHM的结构研究将在几个方面产生很大的影响 研究领域。 他们将提供一个结构模型来测试 提出反应机制，提供药理学信息 帮助生物活性激素的合成，提供第一个 一个新的酶类的结构，也许是一个新的折叠基序， 提供了研究DbM结构和反应机理的模型 通过同源性，并提供了观察到的结构解释 底物特异性

Structural studies of PHM will have a great impact in several areas of research. They will provide a structural model to test proposed reaction mechanisms, provide pharmacological information aiding the synthesis of bioactive hormones, provide the first structure of a novel enzyme class and perhaps a novel folding motif, provide a model to study the structure and reaction mechanism of DbM through homology and provide a structural explanation of the observed substrate specificity.