Center for Computational Biology and Bioinformatics

我们建议建立一个计算生物学和生物信息学中心，作为哥伦比亚研究和教育的中心。该中心将通过培养实验室和计算科学家之间的合作，通过培训计划，研讨会和研讨会，并通过提供必要的计算基础设施和支持，促进计算方法融入生物医学研究的不同领域。内部研究将包括如DNA和蛋白质序列分析，SNP分析及其与人类疾病的关系，蛋白质结构分析，微阵列分析，完整的分析和比较等领域。 基因组，蛋白质的功能注释，相互作用蛋白质网络的研究，以及基于3D结构的新药设计。该中心将通过与参与部门开发联合课程和学位课程，在教育中发挥核心作用。还将建立一个工业推广计划，工业科学家将能够参加中心的讲座、研讨会和讲习班，在中心度过小型休假，并与中心科学家建立研究联系。

We propose to establish a Center for Computational Biology and Bioinformatics that will serve as a focal point for research and education at Columbia. The center will facilitate the integration of computational methods into different areas of biomedical research through the fostering of collaborations between laboratory and computational scientists, through training programs, workshops and seminars, and by providing the computational infrastructure and support that is necessary for cutting-edge research in this area. In-house research will include areas such as DNA and protein sequence analysis, SNP analysis and its relationship to human disease, protein structure analysis, the analysis of microarrays, the analysis and comparison of complete genomes, functional annotation of proteins, the study of networks of interacting proteins, and the 3D structure-based design of new pharmaceuticals. The center will play a central role in education through the development of joint courses and degree programs with participating departments. An industrial outreach program will also be established in which industrial scientists will be able to attend center lectures, symposia and workshops, spend mini-sabbaticals at the center, and establish research contacts with center scientists.