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CONFORMATION OF SMALL PEPTIDES IN SOLUTION

CONFORMATION OF SMALL PEPTIDES IN SOLUTION
溶液中小肽的构象
批准号：
6314233
负责人：
BARRY H HONIG
金额：
$4.36万
依托单位：
COLUMBIA UNIV NEW YORK MORNINGSIDE
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-05-05 至 2002-04-30
来源：
https://reporter.nih.gov/project-details/6314233
关键词：
biological products biomedical resource computers statistics /biometry technology /technique

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英文摘要
DysonandWrighthaveused2DNMRtodeterminetheconformations of small penta-peptides in solution. Remarkably, some of these peptides have a single favored conformation. We are in the process of generating an ensemble of possible conformations and calculating their conformational energies to see if we can account for the experimental observations. If we are successful, we will suggest new peptides to be studied in an attempt to see if our methods have predictive power. This project is one part of a larger effort going on in the Center to elucidate the energetic basis of protein folding and to develop prediction algorithms.
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Structure-informed dissection of cancer-specific intracellular and paracrine networks
Genome-wide structure-based analysis of protein-protein interactions and networks
Genome-wide structure-based analysis of protein-protein interactions and networks
Genome-wide structure-based analysis of protein-protein interactions and networks
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