DISORDERS OF LEXICAL ACCESS IN SPEECH PRODUCTION

言语产生中的词汇使用障碍

基本信息

  • 批准号:
    6523599
  • 负责人:
  • 金额:
    $ 34.49万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2000
  • 资助国家:
    美国
  • 起止时间:
    2000-09-01 至 2005-08-31
  • 项目状态:
    已结题

项目摘要

The goal of the proposed research is to understand the nature of naming and word-finding difficulties in aphasia. The objective is to explain patterns of word production deficits in terms of damage to the cognitive/linguistic mechanisms that underlie normal word production, and then to use this knowledge toward the development of a theory of the functional organization of the brain. Two general questions will be addressed: 1) What are the causes of the grammatical class deficits? And, 2) what are the causes of the different error types in naming deficits? More specific questions include: 1) Are there different subtypes of grammatical class disorders? 2) What is the relationship between impairments in the production of nouns and the ability to produce noun phrase structure? 3) Are the causes of access failure for nouns and verbs the same as for failure to retrieve adjectives? What are the causes of failure to access function words and inflectional morphology? 4) Are different mixtures of error types the result of global lesions that affect equally all stages of the lexical access process or are they the result (at least in some cases) of different lesions to different stages of the process? 5) What relationship is there between the distribution of error types in naming and other tasks (such as reading, repetition, comprehension, etc.)? These and related questions will be addressed through a three-pronged program of research. The most important part involves the detailed investigation of the word and phrase processing performance of English and Italian monolingual aphasics and Spanish-Catalan bilingual aphasics. The two other components of the research involve the computational modeling of the patients' patterns of word production deficits and the experimental investigation of normal subjects' word and phrase production performance. This integrated approach to the study of lexical access deficits should provide important information about the organization and processing structure of the lexicon and about the functional causes of word production disorders in aphasia. These are necessary components of the larger goal of understanding the functional architecture of the brain and for developing intervention strategies for remedial training of aphasia.
这项研究的目的是了解失语症患者命名和找词困难的本质。 其目的是解释模式的文字生产赤字方面的损害认知/语言机制的基础正常的文字生产,然后使用这些知识对大脑的功能组织理论的发展。 本文将探讨两个一般性问题:1)语法类缺陷的原因是什么? 以及,2)在命名缺陷中的不同错误类型的原因是什么? 更具体的问题包括:1)是否存在不同的语法类别障碍亚型?2)名词产生障碍和名词短语结构产生能力之间的关系是什么?3)名词和动词的访问失败的原因与检索形容词失败的原因相同吗?不能理解虚词和屈折形态的原因是什么?4)错误类型的不同混合是整体损害的结果,这些损害同样影响词汇通达过程的所有阶段,还是(至少在某些情况下)对过程的不同阶段的不同损害的结果?5)命名错误类型的分布与其他任务(如阅读、复述、理解等)之间有什么关系? 这些问题和相关问题将通过一个三管齐下的研究计划来解决。最重要的部分是对英语和意大利语单语失语症患者和西班牙语-加泰罗尼亚语双语失语症患者的词和短语加工绩效的详细调查。 研究的另外两个组成部分涉及患者的单词产生缺陷模式的计算建模和正常受试者的单词和短语产生性能的实验研究。 这种综合的方法来研究词汇通达缺陷,应该提供重要的信息组织和处理结构的词汇和失语症的单词产生障碍的功能性原因。 这些都是理解大脑功能结构这一更大目标的必要组成部分,也是制定失语症治疗训练干预策略的必要组成部分。

项目成果

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ALFONSO CARAMAZZA其他文献

ALFONSO CARAMAZZA的其他文献

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{{ truncateString('ALFONSO CARAMAZZA', 18)}}的其他基金

Cortical Organization of Noun and Verb Processing
名词和动词处理的皮质组织
  • 批准号:
    7318344
  • 财政年份:
    2005
  • 资助金额:
    $ 34.49万
  • 项目类别:
Cortical Organization of Noun and Verb Processing
名词和动词处理的皮质组织
  • 批准号:
    7738895
  • 财政年份:
    2005
  • 资助金额:
    $ 34.49万
  • 项目类别:
Cortical Organization of Noun and Verb Processing
名词和动词处理的皮质组织
  • 批准号:
    7533995
  • 财政年份:
    2005
  • 资助金额:
    $ 34.49万
  • 项目类别:
Cortical Organization of Noun and Verb Processing
名词和动词处理的皮质组织
  • 批准号:
    7154060
  • 财政年份:
    2005
  • 资助金额:
    $ 34.49万
  • 项目类别:
Cortical Organization of Noun and Verb Processing
名词和动词处理的皮质组织
  • 批准号:
    7032563
  • 财政年份:
    2005
  • 资助金额:
    $ 34.49万
  • 项目类别:
DISORDERS OF LEXICAL ACCESS IN SPEECH PRODUCTION
言语产生中的词汇使用障碍
  • 批准号:
    6379566
  • 财政年份:
    2000
  • 资助金额:
    $ 34.49万
  • 项目类别:
DISORDERS OF LEXICAL ACCESS IN SPEECH PRODUCTION
言语产生中的词汇使用障碍
  • 批准号:
    6647670
  • 财政年份:
    2000
  • 资助金额:
    $ 34.49万
  • 项目类别:
DISORDERS OF LEXICAL ACCESS IN SPEECH PRODUCTION
言语产生中的词汇使用障碍
  • 批准号:
    6796791
  • 财政年份:
    2000
  • 资助金额:
    $ 34.49万
  • 项目类别:
DISORDERS OF LEXICAL ACCESS IN SPEECH PRODUCTION
言语产生中的词汇使用障碍
  • 批准号:
    6166059
  • 财政年份:
    2000
  • 资助金额:
    $ 34.49万
  • 项目类别:
MECHANISMS OF NEGLECT DYSLEXIA
忽视阅读障碍的机制
  • 批准号:
    2891978
  • 财政年份:
    1996
  • 资助金额:
    $ 34.49万
  • 项目类别:

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