CORE--VIROLOGY FACILITY

病毒学核心实验室的总体目标是提供与艾滋病毒研究相关的全面病毒学测试和服务，向硬件研究人员提供其专门的BSL2/3实验室设施，并开发可能对临床和基础研究有用的新病毒学测试。主要核心服务包括：(1)通过定量微共培养分析人类免疫缺陷病毒的传染性；(2)人类免疫缺陷病毒核糖核酸和DNA分析；(3)艾滋病毒准种的鉴定；(4)耐药性和合胞体诱导能力的表型鉴定；以及(5)艾滋病毒感染者的血液样本和其他生物样本的处理、储存和运输。该中心还将为有意为其硬件项目开发复杂的病毒学程序的研究人员提供培训和技术建议。

The overall objectives of the Virology Core Laboratory are to provide comprehensive virologic tests and services relevant to HIV research, to make available its specialized BSL2/3 laboratory facilities to HW researchers, and to develop new virologic tests that may be useful in clinical and basic research. Major core services include: (1) assays of HW infectivity by means of quantitative micrococultures, (2) assays of HW1 RNA and DNA, (3) characterization of HIV quasispecies, (4) phenotypic characterization of drug resistance and of syncytium-inducing capacity, and (5) processing, storage and shipment of blood specimens and other biological samples from patients with HIV. The core will also provide training and technical advice to researchers interested in developing sophisticated virologic procedures for their HW projects.