CORE--VIROLOGY FACILITY

病毒学核心实验室的总体目标是提供与艾滋病毒研究有关的全面病毒学测试和服务，向卫生保健研究人员提供其专门的BSL2/3实验室设施，并开发可能对临床和基础研究有用的新的病毒学测试。主要的核心服务包括：(1)通过定量微共培养检测HW的传染性，(2)检测HW1 RNA和DNA，(3)鉴定HIV准种，(4)耐药和合胞诱导能力的表型鉴定，(5)处理、储存和运送HIV患者的血液标本和其他生物样品。该中心还将向有兴趣为其HW项目开发复杂病毒学程序的研究人员提供培训和技术咨询。

The overall objectives of the Virology Core Laboratory are to provide comprehensive virologic tests and services relevant to HIV research, to make available its specialized BSL2/3 laboratory facilities to HW researchers, and to develop new virologic tests that may be useful in clinical and basic research. Major core services include: (1) assays of HW infectivity by means of quantitative micrococultures, (2) assays of HW1 RNA and DNA, (3) characterization of HIV quasispecies, (4) phenotypic characterization of drug resistance and of syncytium-inducing capacity, and (5) processing, storage and shipment of blood specimens and other biological samples from patients with HIV. The core will also provide training and technical advice to researchers interested in developing sophisticated virologic procedures for their HW projects.