Pulmonary Diagnosis By Multichannel Lung Sound Analyzer

多通道肺音分析仪进行肺部诊断

• 批准号: 6486222
• 负责人: RAYMOND L H MURPHY
• 金额: $ 10万
• 依托单位: STETHOGRAPHICS, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2002-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6486222
• 关键词: biomedical equipment development; clinical research; clinical trials; computer assisted diagnosis; computer system design /evaluation; diagnosis design /evaluation; heart failure; human subject; lung disorder; patient oriented research; pneumonia; psychoacoustics; respiratory disorder diagnosis; sound; sound frequency

DESCRIPTION (Applicant's abstract): Medical personnel routinely use the acoustic stethoscope to listen to lung sounds because the sounds provide important clinical information. These sounds are complex signals that reflect the underlying pulmonary pathophysiology. Unfortunately, studies of auscultation of the chest consistently show significant observer variability casting doubt on its clinical reliability. We developed user friendly, practical computerized technologies to obtain the important information provided by the sounds. Our results have been validated, patented, presented at scientific meetings and published in prominent journals. Our method provides objective, reliable information not previously possible to obtain with the human ear. It can be used even in severely ill patients. We are confident that automated lung sound analysis will replace the acoustic stethoscope in many of its current applications and become the new standard. In Phase I, we plan to determine whether our preliminary observations are correct that the acoustic patterns found in patients with heart failure are significantly different than those found in pneumonia. As a treatment of these very common disorders are different, more accurate diagnosis can have significant clinical and monetary benefit. In Phase II we will optimize our methods and demonstrate the value of automated lung sound analysis in broader clinical trials. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述（申请人摘要）：医务人员日常使用

项目成果

Automated lung sound analysis in patients with pneumonia.

肺炎患者的自动肺音分析。

• 发表时间: 2004
• 期刊: Respiratory care.
• 作者: Murphy,RaymondLH;Vyshedskiy,Andrey;Power-Charnitsky,Verna-Ann;Bana,DhirendraS;Marinelli,PatriciaM;Wong-Tse,Anna;Paciej,Rozanne
• 通讯作者: Paciej,Rozanne

Transmission of crackles in patients with interstitial pulmonary fibrosis, congestive heart failure, and pneumonia.

间质性肺纤维化、充血性心力衰竭和肺炎患者中爆裂音的传播。

• DOI: 10.1378/chest.128.3.1468
• 发表时间: 2005
• 期刊: Chest
• 影响因子: 9.6
• 作者: Vyshedskiy,Andrey;Bezares,Francisco;Paciej,Rozanne;Ebril,Margo;Shane,John;Murphy,Raymond
• 通讯作者: Murphy,Raymond