Diabetes Research for Pediatric Endocrinologists

儿科内分泌学家的糖尿病研究

• 批准号: 6584802
• 负责人: GEORGEANNA J KLINGENSMITH
• 金额: $ 28.63万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6584802
• 关键词: curriculum; diabetes education; diabetes mellitus; education evaluation /planning; endocrinology; health science research support; pediatrics

DESCRIPTION (provided by applicant): This application is part of a combined application for training of pediatric endocrinology fellows and junior pediatric endocrinology faculty. This training program is designed to provide multidisciplinary training in diabetes research at The Barbara Davis Center (BDC) and The University of Colorado Health Sciences Center (UCHSC).This proposal's rationale is: 1) there is a critical shortage of pediatric endocrinologists in the country, particularly those trained and experienced in diabetes research 2) Diabetes is an increasingly significant healthcare problem in the pediatric population with devastating consequences from a personal and health economic point of view into the future. 3) Current rapid advances in diabetes investigation calls for an increased pool of physician scientists trained in clinical, biochemical, epidemiological, and behavioral research to carry out translation research in pediatric type 1 and type 2 diabetes to bring advances in diabetes research to the clinical arena. The Barbara Davis Center has extensive and a proven record in research training of young investigators. The BDC and UCHSC have a well established network of investigators working in the immunobiology, genetics, and molecular biology of type 1 diabetes, as well as the abnormal pathophysiology of type 2 diabetes. This network of experienced mentors is ideally suited to develop the next generation of young pediatric endocrinologists into independent diabetes investigators. Areas of research focus within The Barbara Davis Center include islet cell physiology, genetics, molecular biology, transplant immunology, and the autoimmunity, prediction and prevention of type 1 diabetes, and the epidemiology, prevention and treatment of type 1 and type 2 diabetes. This application is enhanced by the NIH supported Diabetes and Endocrinology Research Center, well established, NIH supported Pediatric and Adult Clinical Research Centers, and a Clinical Nutrition Research Unit, an NIH supported K30 Clinical Research Curriculum Award, as well as a strong Masters of Science in Public Health Program. This application has the support of the Departments of Pediatrics, Medicine, Preventive Medicine and The Children's Hospital of Denver. The ability to provide strong didactic coursework in statistics, epidemiology, research methods, ethics and regulation of human research, medical writing, biochemistry, pharmacokinetics and molecular biology, as well as human medical genetics and molecular genetics through the Program in Clinical Science, combined with a strong mentoring faculty at the BDC and UCHSC will allow us to provide the continuous training and development of young pediatric endocrinologists through their training and development into independent investigators, capable of being competitive for independent research funding and research activity. Other programs within UCHSC which will be supportive of this program include the Program in Human Genetics, The Immune Tolerance Network and the Autoimmune Prevention Center.

描述（由申请人提供）： 该应用是用于培训儿科内分泌研究员和初级儿科内分泌学院的一部分。该培训计划旨在在芭芭拉·戴维斯中心（BDC）和科罗拉多大学健康科学中心（UCHSC）的糖尿病研究中提供多学科培训。该提议的理由是：1）在国家中培训和糖尿病研究中越来越多的糖尿病研究中的儿科内分泌学家的严重短缺，糖尿病是一个越来越多的糖尿病研究2）从个人和健康经济的角度到未来的毁灭性后果。 3）目前的糖尿病研究快速进步要求接受接受临床，生化，流行病学和行为研究培训的医师科学家，以进行1型小儿1型糖尿病和2型糖尿病的翻译研究，以将糖尿病研究的进步带到临床领域。芭芭拉·戴维斯中心（Barbara Davis Center）在年轻研究人员的研究培训中拥有广泛的记录。 BDC和UCHSC具有1型糖尿病的免疫生物学，遗传学和分子生物学的研究人员网络，以及2型糖尿病的异常病理生理学。这个经验丰富的导师网络非常适合将下一代年轻的儿科内分泌学家发展成为独立的糖尿病研究人员。芭芭拉·戴维斯中心（Barbara Davis Center）内部的研究重点包括胰岛细胞生理学，遗传学，分子生物学，移植免疫学以及1型糖尿病的自身免疫性，预测和预防，以及1型和1型和2型糖尿病的流行病学，预防和治疗。 NIH支持的糖尿病和内分泌研究中心，建立良好的NIH支持儿科和成人临床研究中心以及临床营养研究部门，NIH支持K30临床研究课程奖，以及公共卫生计划中强大的科学硕士。该申请得到了儿科，医学，预防医学和丹佛儿童医院的支持。在统计学，流行病学，研究方法，伦理和人类研究，医学写作，生物化学，药代动力学和分子生物学以及人类的医学遗传学和分子遗传学中，通过临床科学的计划与BDC的强大训练可以允许Uchs的强大辅导，能够在统计学，流行病学，研究方法，伦理和调节中提供强大的教学课程。内分泌学家通过对独立研究人员进行培训和发展，能够在独立的研究资金和研究活动中竞争。 UCHSC中支持该计划的其他计划包括人类遗传学，免疫耐受性网络和自身免疫预防中心。