Oxide Glass Fiber Optimized for Short Pulse IR Lasers

针对短脉冲红外激光器优化的氧化物玻璃光纤

• 批准号: 6443577
• 负责人: DANH C TRAN
• 金额: $ 12.24万
• 依托单位: INFRARED FIBER SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6443577
• 关键词: biomedical equipment development; fiber optics; germanium; infrared radiation; laser therapy; lasers; oxides; technology /technique development

There is a clinical need for optimized optical fiber transmission of short pulse mid-infrared laser radiation for surgical laser applications. Large potential medical markets such as cosmetic skin resurfacing, dentistry, and ophthalmology utilize the Er: YAG and Er:YSGG lasers for therapeutic procedures. The goal of this Phase I study is to further develop the germanium oxide glass fibers made by IFS so that they may be used in these applications. There are three aims of this study: (1) Testing and development of fibers using a short-pulse ER:YAG laser for potential ophthalmic applications requiring further precision, (2) Testing at high-power, high pulse repetition rates for dental and cosmetic applications requiring rapid removal of large amounts of tissue, and (3) development of more compatible germanium oxide fibers. Further Phase II work will be done on the continued fiber development and the development of specialized fiber probe tip designs for flexible delivery of laser radiation during custom surgical laser procedures. PROPOSED COMMERCIAL APPLICATIONS: IR fiber able to deliver laser energy from short pulse mid-infrared lasers would have many applications in laser surgery and dentistry, including ophthalmology and dermatology, for example.

临床上需要优化短脉冲中红外激光辐射的光纤传输，以用于外科激光应用。巨大的潜在医疗市场，如美容换肤，牙科和眼科利用Er：YAG和Er：YSGG激光器进行治疗程序。第一阶段研究的目标是进一步开发IFS制造的氧化锗玻璃纤维，使其可用于这些应用。本研究有三个目的：（1）使用短脉冲ER：YAG激光器测试和开发光纤，用于需要更高精度的潜在眼科应用，（2）在需要快速去除大量组织的牙科和美容应用中测试高功率，高脉冲重复率，以及（3）开发更兼容的氧化锗光纤。进一步的第二阶段工作将在持续的光纤开发和专用光纤探头尖端设计的开发上完成，以便在定制的外科激光手术期间灵活地输送激光辐射。拟议的商业应用：能够从短脉冲中红外激光器传递激光能量的IR光纤将在激光外科和牙科（包括例如眼科和皮肤科）中具有许多应用。

项目成果

Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation.

用于内窥镜传输铒：YAG 激光辐射的混合锗/石英光纤。

• DOI: 10.1002/lsm.10249
• 发表时间: 2004
• 期刊: Lasers in surgery and medicine.
• 作者: Chaney,CharlesA;Yang,Yubing;Fried,NathanielM
• 通讯作者: Fried,NathanielM

Optimization of the Erbium:YAG laser for precise incision of ureteral and urethral tissues: in vitro and in vivo results.

优化铒:YAG 激光精确切割输尿管和尿道组织：体外和体内结果。

• DOI: 10.1002/lsm.10205
• 发表时间: 2003
• 期刊: Lasers in surgery and medicine.
• 作者: Fried,NathanielM;Tesfaye,Zelalem;Ong,AlbertM;Rha,KoonH;Hejazi,Pooya
• 通讯作者: Hejazi,Pooya

Erbium:YAG laser lithotripsy using hybrid germanium/silica optical fibers.

使用混合锗/石英光纤进行铒：YAG 激光碎石术。

• DOI: 10.1089/end.2004.18.830
• 发表时间: 2004
• 期刊: Journal of endourology
• 影响因子: 2.7
• 作者: Yang,Yubing;Chaney,CharlesA;Fried,NathanielM
• 通讯作者: Fried,NathanielM