AIDS RELATED RESEARCH CAGING

描述（由申请人提供）： ONPRC建议购买适合用于艾滋病相关研究的SPF雄性印度恒河猴（Macaca mulatta）的笼子。 在ONPRC和全国范围内，对SPF恒河猴用于艾滋病相关研究的需求不断增加，已经超过了扩大生产群以供应更多动物的供应努力，这使得必须保留雌性后代用于繁殖，使得雄性SPF恒河猴成为艾滋病相关研究项目的主要模型。 动物生物安全2级和3级（ABLS 2和ABSL 3）收容设施在ONPRC饲养用于艾滋病相关研究的动物，没有配备适合第4组雄性恒河猴的笼子。 现有的笼子没有6.0平方米。英尺美国农业部要求的建筑面积，不提供社会住房的选择。 用于艾滋病相关研究的动物有机会体验丰富的社会环境是非常重要的。 本申请中要求的是6.2平方英尺。英尺符合美国农业部对第4组雄性恒河猴要求的笼子和相关设备，并为艾滋病相关研究中使用的NHP的环境富集和社会住房提供广泛的选择。

DESCRIPTION (provided by applicant): The ONPRC proposes to purchase caging suitable for housing SPF male Indian-origin rhesus macaques (Macaca mulatta) used in AIDS related research. Increasing demands for SPF rhesus macaques for AIDS related research at the ONPRC and nationally has exceeded the supply efforts to expand production colonies to supply more animals has necessitated retention of female offspring for breeding, leaving male SPF rhesus macaques as the primary model for AIDS-related research projects. The Animal Biosafety Level 2 and 3 (ABLS2 and ABSL3) containment facility which houses animals for AIDS-related research at the ONPRC is not equipped with cages suitable for Group 4 male rhesus macaques. The existing cages do not have the 6.0 sq. ft. of floor space required by USDA and do not provide the option of social housing. It is very important that animals used in AIDS-related research have the opportunity to experience an enriched social environment. Requested in this application are 6.2 sq. ft. cages and associated equipment that will comply with USDA requirements for Group 4 male rhesus macaques and provide a wide range of options for environmental enrichment and social housing of NHPs used in AIDS-related research.