RHESUS CORRAL UPGRADE

描述(由申请人提供)： 改造项目是ONPRC扩大猕猴生产的长期计划的一部分。这项申请的具体目的是改变和翻新已有30年历史的设施，这些设施与六个1英亩的畜栏相关，这些畜栏容纳着SPF的印度恒河猴繁殖群体。继续将畜栏用于恒河猴生产是受到下列因素的推动：1)研究项目的增长和分配给项目的HHP数量的增加需要大幅增加可用HHP的数量；2)ONPRC是国家资源，必须向中心以外的研究人员提供访问；3)长期计划要求将SPF育种计划翻一番，以创造一个自我维持的HEP供应；4)必须扩大动物收容所的储备能力，以便进行适当的动物管理；5)在一个复杂和环境丰富的社会结构中，动物收容所是饲养和饲养动物进入成年期的一种具有成本效益的方法。畜栏中的动物被用作青少年(艾滋病、传染病、发育神经生物学研究项目)、成年动物(免疫学、神经科学和生殖研究项目)和退休饲养员(老龄研究项目)。畜栏设施的翻新将使它们适合长期使用，包括：1)将4号畜栏和5号畜栏之间的储存区改造为5号畜栏的庇护饲养区；2)将现有的5号畜栏饲养区改为安全处理动物的区域；3)升级所有猕猴饲养区的基础设施(电力服务、生活用水、卫生下水道)；4)更换所有饲养区和保养区破旧的屋顶；5)更换所有建筑物上损坏和磨损的金属板；6)修复和重新密封所有饲养区和保留区的混凝土；7)在所有饲养区和等候区安装额外的辐射加热器和灯；8)安装用于冲洗系统的水压增压泵；9)在所有饲养区增加栖息处；10)更换所有畜栏内日益恶化的动物繁殖设备。这项申请将提供资金，用于翻新与六个一英亩畜栏有关的设施。为了继续使用畜栏来扩大猕猴的生产，并符合美国农业部(USDA)的政策和动物福利法(AWA)的规定，翻修是必要的。

DESCRIPTION (provided by applicant): The renovation project is part of a long-range plan to expand rhesus macaque (Macaca mulatta) production at the ONPRC. The specific aim of this application is to alter and renovate the 30-year-old facilities associated with six one-acre corrals that hold SPF Indian rhesus macaque breeding colonies. The continued use of the corrals for rhesus macaque production is driven by the following: 1) the growth in research projects and the numbers of NHPs assigned to projects requires a substantial increase in the number of available NHPs; 2) the ONPRC is a national resource and must provide accessibility to investigators outside of the Center; 3) the long-range plan calls for the doubling of SPF breeding program to create a self-sustaining supply of NHPs; 4) the reserve capacity for animal housing must be expanded for proper animal management; and 5) the corrals are a cost effective method for breeding and raising animals into adulthood in a complex and environmentally rich social structure. Animals in the corrals are used as juveniles (research programs in AIDS, infectious diseases, developmental neurobiology), adults (research programs in immunology, neuroscience and reproduction) and retired breeders (research programs in aging). The renovation of the corral facilities will make them suitable for long-term use and includes the following: 1) convert the storage area between corrals four and five into a sheltered feeding area for corral five; 2) convert the existing corral five feeding area into an area for safe handling of animals; 3) upgrade the infrastructure (electric service, domestic water, sanitary sewer) for all rhesus corral facilities; 4) replace the deteriorated roofs on all feeding and holding areas; 5) replace damaged and worn metal panels on all structures; 6) repair and reseal concrete in all feeding and holding areas; 7) install additional radiant heaters and lights in all feeding and holding areas; 8) install a water pressure booster pump for wash down systems; 9) add perching to all feeding areas; and 10) replace deteriorating animal enrichment equipment in all corrals. This application will provide funds for the renovation of facilities associated with six one-acre corrals. The renovation is necessary for continued use of the corrals to expand rhesus macaque production and to comply with United States Department of Agriculture (USDA) policies and provisions of the Animal Welfare Act (AWA).