Divided Loyalties:Conflicts of Interest in Medicine

描述(由申请人提供)： 现代医学为医生和医学研究人员提供了 通过以下方式显著提高其财务利益的机会 创业冒险。有很多关于金融方面的讨论 医学和法律文献中的利益冲突，以及许多 专业协会正在制定政策，以应对 他们。与利益冲突有关的政府法规和法律 不包括关于以下类型的禁止要求 可能持有的经济利益。机构政策要求各不相同。 没有针对这些人的最新、全面的文件或政策指导 从事医疗保健、医学研究或制定政策以进行审查 关于处理利益冲突的适当手段。这个 挑战是建立一种机制，使新的压力、动机和 在医学研究和临床实践中引入的激励措施可以 与传统的科学原则和伦理价值观相一致 增进公众福祉。这是拟议项目的重点， 使其有别于以前的工作。该项目将把冲突划分为 医生和生物医学研究人员面临的兴趣分为两类- A)在研究环境中发生的情况和B)在临床中发现的情况 练习一下。在这两个领域中，每个领域都将有：1)深入的 对报告的案件和现有文献中涉及冲突的探讨 所有来源的兴趣；2)对方法的透彻分析和批评 医学界已采取措施处理这些冲突，包括 政府法规和立法，以及由 专业组织；3)法律分析 患者、医生和研究人员之间的关系，无论是在 现有的判例以及立法和监管补救办法；以及4)伦理 审查和分析现有的规章制度和准则。变化 在现有的法律、法规和指导方针中将提出建议。最终产品 研究产生的CT将包括同行评议的期刊文章和 为大学出版社准备的一本书。

DESCRIPTION (provided by applicant): Modern medicine has provided physicians and medical researchers with opportunities to enhance significantly their financial interests through entrepreneurial adventures. There has been much discussion of financial conflicts of interest in the medical and legal literature, and many professional societies are in the process of developing policies to deal with them. Governmental regulations and laws concerning conflicts of interest do not encompass requirements that are proscriptive regarding the types of financial interest that may be held. Institutional policy requirements vary. There is no current, comprehensive document or policy guidance for those engaged in health care, medical research, or policy making to review concerning the appropriate means by which to handle conflicts of interest. The challenge is to develop mechanisms whereby the new pressures, motivations, and incentives introduced in medical research and clinical practice can be reconciled with traditional scientific principles and ethical values that promote the public well-being. This is the focus of the proposed project and distinguishes it from previous work. The project will divide conflicts of interest faced by physicians and biomedical researchers into two categories - A) those occurring in research settings and B) those found in clinical practice. Within each of the two areas, there will be: 1) an in-depth exploration of reported cases and existing literature involving conflicts of interest from all sources; 2) a thorough analysis and critique of the approach the medical community has taken to deal with those conflicts, including governmental regulations and legislation, as well as guidelines set out by professional organizations; 3) a legal analysis of the foundations of the relationships among patients, physicians, and researchers, both in terms of existing jurisprudence and legislative and regulatory remedies; and 4) ethical review and analysis of existing rules and regulations and guidelines. Change in existing laws, regulations and guidelines will be proposed. Final products resulting Ct from the research will include peer reviewed journal articles and a book intended for a university press.