NONLINEAR MODEL OF HIPPOCAMPUS

前庭-眼反射(VOR)对 在积极的运动中稳定视力通常是不被认识的， 直到病理损害VOR表现到足以干扰 动态视觉敏锐度。我们已经开发了VOR建模技术， 允许临床医生客观地评估患者的VOR功能。 在过去的一年中，我们扩展了这些建模技术，以包括 目的在治疗过程中进行监测。我们引入了一项新的措施 基于运动员提高自身能力的“超常表现” 通过运动疗法提高动态视力。通过对他们的 VORS在治疗期间，我们能够监测和预测改善 在运动表现中的动态视觉敏锐度。轻度头部 运动过程中的损伤通常表现为视力下降 由VOR进行稳定。两名职业橄榄球运动员是 目前正在用我们的建模技术进行测试。此外， 弗吉尼亚大学对100名运动员进行了一项研究，使用我们的 VOR建模技术。一篇运动生理学博士论文 这所大学的基础是重新测试这些VORS的子集 运动员头部受轻伤后。我们扩展了我们对 VOR的宽带特性在人体研究中的应用 在行走/跑步时。初步结果描述了一个重要的 我们预计VOR的低频频道将扮演新的角色 将导致预防老年人跌倒的重点治疗。

The importance of the vestibulo-ocular reflex (VOR) for stabilizing vision during active movements is generally unrecognized, until pathology impairs VOR performance sufficiently to interfere with dynamic visual acuity. We have developed VOR modeling techniques that allow clinicians to evaluate patients VOR function objectively. During the past year, we extended these modeling techniques to include objective monitoring during therapy. We introduced a new measure of "super performance" based on athletes' abilities to improve their dynamic visual acuity through exercise therapy. By modeling their VORs during therapy, we are able to monitor and predict improvements in dynamic visual acuity during athletic performance. Mild head injury during sports performance often shows up as decreased visual stabilization by the VOR. Two professional football tams are currently being tested with our modeling techniques. In addition, the University of Virginia conducted a study of 100 athletes, using our VOR modeling techniques. A doctoral thesis in Exercise Physiology at that university is based on re-testing the VORs of a subset of these athletes after mild head injury. We extended our analysis of the broad-band characteristics of the VOR to studies of human subjects during walking/running. The preliminary results describe an important new role for lower-frequency channels of the VOR, that we anticipate will lead to focused therapy for preventing falls in the elderly.