DETERMINE HEAT DEPOSITION BY MRI COILS

17 O去耦的标准方法使用自旋回波序列 因此需要体积线圈用于适当的实现。 我们 已经开发出一种脉冲序列，允许17O去耦期间， 质子刺激回波（STEAM）序列。 这允许使用 双调谐表面线圈用于17O定量。 使用表面 线圈具有优于使用体积线圈的几个优点， 包括改善信噪比和适合研究 小体积的组织。 我们已经成功探测到 自然丰度17O在动物使用此序列。 进一步 对序列的改进正在进行中，包括适应 多体素光谱和成像。

The standard method of 17O decoupling uses a spin-echo sequence and therefore requires a volume coil for proper implementation. We have developed a pulse sequence that allows 17O decoupling during a proton stimulated echo (STEAM) sequence. This allows use of a double-tuned surface coil for 17O quantification. Use of a surface coil carries several advantages over the use of a volume coil, including improved signal-to-noise ratios and suitability for studying small volumes of tissue. We have successfully detected natural-abundance 17O in animals using this sequence. Further improvements to the sequence are underway, including adaptation for multi-voxel spectroscopy and imaging.