DETERMINE HEAT DEPOSITION BY MRI COILS

17O去耦合的标准方法使用自旋回波序列 因此需要音量线圈才能正确实现。我们 已经开发出一种脉冲序列，允许在17O期间进行去耦合 质子激发回声(STEAM)序列。这允许使用 双调谐表面线圈，用于17O定量。曲面的使用 线圈与使用卷线圈相比具有几个优点， 包括改进的信噪比和研究的适宜性 少量的组织。我们已经成功地检测到 自然--使用该序列的动物体内的丰度为17O。进一步 对序列的改进正在进行中，包括对 多体素光谱学和成像。

The standard method of 17O decoupling uses a spin-echo sequence and therefore requires a volume coil for proper implementation. We have developed a pulse sequence that allows 17O decoupling during a proton stimulated echo (STEAM) sequence. This allows use of a double-tuned surface coil for 17O quantification. Use of a surface coil carries several advantages over the use of a volume coil, including improved signal-to-noise ratios and suitability for studying small volumes of tissue. We have successfully detected natural-abundance 17O in animals using this sequence. Further improvements to the sequence are underway, including adaptation for multi-voxel spectroscopy and imaging.