Molecular Imaging: Training for Oncology

分子成像：肿瘤学培训

• 批准号: 6647139
• 负责人: Hedvig Hricak
• 金额: $ 53.44万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-16 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6647139
• 关键词: bioimaging /biomedical imaging; clinical research; education evaluation /planning; imaging /visualization /scanning; molecular oncology; training

DESCRIPTION (provided by applicant): The goal of this program is to train a new generation of researchers, to become facile with both the biology and the technology of "molecular imaging". The term "molecular imaging" has been applied to imaging techniques that combine benefits from 2 complementary scientific developments, namely, 1) the improving technology of imaging leading to ever more versatile and high resolution imaging modalities for both laboratory and clinical applications; 2) advances in understanding of cancer biology which are exploited to create imaging probes for the key molecules and related biochemical events that are fundamental to neoplasia. As knowledge increases, interdisciplinary training will be needed, if these advances are going to be quickly translated into cancer discovery. At Memorial Sloan-Kettering Cancer Center (MSKCC), there has been rapid growth in molecular imaging capabilities and resources fueled by NCI funded initiatives including the P50 In Vivo Cellular and Molecular Imaging Center (ICMIC), the small animal imaging resource program (SAIRP), and multiple oncology directed PO1 's, SPORES, and RO1's that stress the multimodality biologic imaging of cancer. This "team science" experience suggests that training is required from 2 distinct points of perspectives: clinical researchers need more molecular biology and training in laboratory imaging methods; basic researchers need training in specialized imaging methods, and a more focused and relevant clinical oncology perspective. This R25T program is designed to meet these diverse training needs. The program will be managed through an internal advisory committee consisting of clinical and basic faculty with experience in graduate medical education in oncology. Mentors will be drawn from a distinguished group of NCI supported cancer researchers. Both basic and clinical trainees will be recruited, with emphasis on equal opportunities for minorities. A specialized curriculum will include the relevant molecular biology, research methodology, instruction in advanced imaging methods, and an individualized research program of basic, translational and clinical.

描述（由申请人提供）：该项目的目标是培养新一代研究人员，使其熟悉生物学和“分子成像”技术。 “分子成像”一词已应用于结合了两种互补的科学发展的优势的成像技术，即：1）成像技术的改进为实验室和临床应用带来了更加通用和高分辨率的成像模式； 2）对癌症生物学理解的进步，可用于为肿瘤形成的关键分子和相关生化事件创建成像探针。 随着知识的增加，如果这些进步要迅速转化为癌症发现，就需要跨学科培训。 在纪念斯隆-凯特琳癌症中心 (MSKCC)，在 NCI 资助的计划的推动下，分子成像能力和资源得到了快速增长，这些计划包括 P50 体内细胞和分子成像中心 (ICMIC)、小动物成像资源计划 (SAIRP) 以及强调癌症多模态生物成像的多种肿瘤学导向的 PO1、SPORES 和 RO1。 这种“团队科学”的经验表明，需要从两个不同的角度进行培训：临床研究人员需要更多的分子生物学和实验室成像方法的培训；基础研究人员需要专业成像方法的培训，以及更有针对性和相关的临床肿瘤学视角。 此 R25T 计划旨在满足这些多样化的培训需求。该计划将通过一个内部咨询委员会进行管理，该委员会由具有肿瘤学研究生医学教育经验的临床和基础教师组成。 导师将来自 NCI 支持的杰出癌症研究人员小组。 将招募基础和临床学员，重点是少数族裔机会平等。 专业课程将包括相关的分子生物学、研究方法、先进成像方法的指导以及基础、转化和临床的个性化研究计划。