Molecular Imaging: Training for Oncology

描述(由申请者提供)：这是2002年开始的纪念斯隆-凯特琳癌症中心(MSKCC)R25T培训资助计划“分子成像：肿瘤学培训”(MITO)的续签申请。在过去的五年里，分子成像已经被确立为一种杰出的工具，用于促进实验室发现的快速进步以及独特的个性化患者护理。我们计划的目标是培养新一代成像研究人员，他们在现代癌症生物学和成像技术方面都足够熟练，能够引领分子成像作为肿瘤学实验室发现和个性化临床护理的工具的快速发展。该计划由一个内部咨询委员会管理，该委员会由具有肿瘤学研究生医学教育经验的临床和基础癌症研究人员组成。由领先的分子成像研究人员组成的杰出的外部顾问委员会提供持续的反馈和建议。作为世界领先的临床癌症中心之一，MSKCC提供了一个独特的环境，该中心与一个研究机构(斯隆-凯特琳研究所[SKI])紧密结合。它拥有广泛的分子成像基础设施，以及多个肿瘤学导向的PO1、孢子和RO1，具有集成的成像组件，强调癌症的多模式生物成像。这些研究计划为培训和为学员选择项目提供了肥沃的土壤。导师来自NCI支持的癌症研究人员的杰出教职员工。我们的培训计划利用了我们在分子成像小组和癌症生物学、肿瘤免疫学、分子病理学和分子药理学方面的基础实验室计划之间建立的关系。它还利用了MSKCC在过去五年中启动的翻译计划，用于图像引导介入、临床PET研究、回旋加速器放射化学和包括生物标记物评估在内的高级图像分析。专业课程包括基础研究、转化性研究或临床跨学科研究以及相关的分子生物学、研究方法论和高级成像方法的个性化研究计划。来自康奈尔医学院、滑雪学院和洛克菲勒大学的三所院校的研究生项目提供教学培训。我们的多样性增进计划为少数族裔和妇女提供平等机会，包括一个Mito少数族裔招募委员会，MSKCC多样性干事的参与，以及CCNY/MSKCC伙伴关系的领导。基础科学和临床实习生都将被招募。一项计划已经到位，以促进我们的受训人员在全国各地的学术机构作为分子成像项目的初级教员。

DESCRIPTION (provided by applicant): This is a renewal application for the Memorial Sloan-Kettering Cancer Center (MSKCC) R25T training grant program, "Molecular Imaging: Training for Oncology" (MITO), which began in 2002. In the last five years, molecular imaging has been established as an outstanding tool for fostering rapid progress in laboratory discovery as well as uniquely individualized patient care. The goal of our program is to train a new generation of imaging researchers, who are sufficiently facile in both modern cancer biology and imaging techniques to lead the rapid development of molecular imaging as a tool for laboratory discovery and individualized clinical care in oncology. The program is managed by an internal advisory committee composed of clinical and basic cancer researchers with experience in graduate medical education in oncology. A distinguished external advisory board composed of leading molecular imaging researchers provides continual feedback and advice. MSKCC offers a unique environment as one of the leading clinical cancer centers in the world that is closely integrated with a research institution (Sloan-Kettering Institute [SKI]). It has an extensive molecular imaging infrastructure, as well as multiple oncology directed PO1s, SPOREs and RO1s with integral imaging components that stress the multimodality biologic imaging of cancer. These research programs provide fertile ground for training and selecting projects for trainees. Mentors are drawn from a distinguished faculty of NCI-supported cancer researchers. Our training program makes use of relationships we have established between the molecular imaging group and basic laboratory programs in cancer biology, tumor immunology, molecular pathology, and molecular pharmacology. It also makes use of translational programs that have been initiated at MSKCC over the last five years, in image-guided intervention, clinical PET research, cyclotron radiochemistry and advanced image analysis including biomarker assessment. A specialized curriculum includes an individualized research program of basic, translational or clinical interdisciplinary research and the relevant molecular biology, research methodology, and advanced imaging methods. Tri-institutional graduate programs from Cornell Medical College, SKI and Rockefeller University provide didactic training. Our diversity enhancement plan offers equal opportunities for minorities and women and includes a MITO Minority Recruitment Committee, participation of the MSKCC Diversity officer, and leadership from the CCNY/MSKCC Partnership. Both basic science and clinical trainees will be recruited. A plan is in place to facilitate placement of our trainees as junior faculty in molecular imaging programs at academic institutions across the country.