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Molecular Imaging: Training for Oncology

分子成像：肿瘤学培训

基本信息

批准号：
8543545
负责人：
Hedvig Hricak
金额：
$ 49.82万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-08-16 至 2015-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8543545
关键词：
Advisory Committees Basic Science Biological Markers Cancer Biology Clinic Clinical Clinical Cancer Center Country Cyclotrons Detection Development Educational Curriculum Environment Event Faculty Feedback Fellowship Fostering Future Generations Goals Grant Image Image Analysis Imaging Techniques Institutes Institution Interdisciplinary Study Laboratories Lead Leadership Maintenance Malignant Neoplasms Memorial Sloan-Kettering Cancer Center Mentors Minority Molecular Molecular Biology Patient Care Pharmacology Positron-Emission Tomography Postdoctoral Fellow Radiochemistry Recruitment Activity Research Research Infrastructure Research Methodology Research Personnel Research Project Grants Scientist Stress Technology Training Training Programs Translational Research Universities Woman anticancer research cancer imaging clinical care experience graduate medical education image guided intervention imaging modality medical schools molecular imaging molecular pathology multimodality neoplastic oncology programs tool tumor immunology tumorigenesis

项目摘要

This is a renewal application for the Memorial Sloan-Kettering Cancer Center (MSKCC) R25T training grant program, "Molecular Imaging: Training for Oncology" (MITO), which began in 2002. In the last five years, molecular imaging has been established as an outstanding tool for fostering rapid progress in laboratory discovery as well as uniquely individualized patient care. The goal of our program is to train a new generation of imaging researchers, who are sufficiently facile in both modern cancer biology and imaging techniques to lead the rapid development of molecular imaging as a tool for laboratory discovery and individualized clinical care in oncology. The program is managed by an internal advisory committee composed of clinical and basic cancer researchers with experience in graduate medical education in oncology. A distinguished external advisory board composed of leading molecular imaging researchers provides continual feedback and advice. MSKCC offers a unique environment as one of the leading clinical cancer centers in the world that is closely integrated with a research institution (Sloan-Kettering Institute [SKI]). It has an extensive molecular imaging infrastructure, as well as multiple oncology directed PO1s, SPOREs and RO1s with integral imaging components that stress the multimodality biologic imaging of cancer. These research programs provide fertile ground for training and selecting projects for trainees. Mentors are drawn from a distinguished faculty of NCI-supported cancer researchers. Our training program makes use of relationships we have established between the molecular imaging group and basic laboratory programs in cancer biology, tumor immunology, molecular pathology, and molecular pharmacology. It also makes use of translational programs that have been initiated at MSKCC over the last five years, in image-guided intervention, clinical PET research, cyclotron radiochemistry and advanced image analysis including biomarker assessment. A specialized curriculum includes an individualized research program of basic, translational or clinical interdisciplinary research and the relevant molecular biology, research methodology, and advanced imaging methods. Tri-institutional graduate programs from Cornell Medical College, SKI and Rockefeller University provide didactic training. Our diversity enhancement plan offers equal opportunities for minorities and women and includes a MITO Minority Recruitment Committee, participation of the MSKCC Diversity officer, and leadership from the CCNY/MSKCC Partnership. Both basic science and clinical trainees will be recruited. A plan is in place to facilitate placement of our trainees as junior faculty in molecular imaging programs at academic institutions across the country.

这是纪念斯隆-凯特琳癌症中心（MSKCC）R25 T培训资助计划“分子成像：肿瘤学培训”（MITO）的续签申请，该计划于2002年开始。在过去的五年中，分子成像已被确立为促进实验室发现以及独特的个性化患者护理快速进展的杰出工具。我们计划的目标是培养新一代的成像研究人员，他们在现代癌症生物学和成像技术方面都足够轻松，以领导分子成像的快速发展，作为肿瘤学实验室发现和个性化临床护理的工具。该计划由一个内部咨询委员会管理，该委员会由具有肿瘤学研究生医学教育经验的临床和基础癌症研究人员组成。由领先的分子成像研究人员组成的杰出外部咨询委员会提供持续的反馈和建议。MSKCC提供了一个独特的环境，作为世界领先的临床癌症中心之一，与研究机构（斯隆-凯特琳研究所[SKI]）紧密结合。它具有广泛的分子成像基础设施，以及多个肿瘤学导向的PO 1，SPORE和RO 1，具有集成的成像组件，强调癌症的多模态生物成像。这些研究项目为学员的培训和选择项目提供了肥沃的土壤。导师是从一个杰出的教师NCI支持的癌症研究人员。我们的培训计划利用我们在分子成像组和癌症生物学，肿瘤免疫学，分子病理学和分子药理学的基础实验室课程之间建立的关系。它还利用了MSKCC在过去五年中启动的翻译计划，包括图像引导干预，临床PET研究，回旋加速器放射化学和高级图像分析，包括生物标志物评估。专业课程包括基础，转化或临床跨学科研究的个性化研究计划以及相关的分子生物学，研究方法和先进的成像方法。康奈尔医学院、SKI和洛克菲勒大学的三机构研究生课程提供教学培训。我们的多元化增强计划为少数族裔和妇女提供平等机会，包括MITO少数族裔招聘委员会，MSKCC多元化官员的参与以及CCNY/MSKCC伙伴关系的领导。基础科学和临床实习生都将被招募。一个计划是在地方，以促进我们的学员作为初级教师在全国各地的学术机构的分子成像计划的安置。

项目成果

期刊论文数量（22）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

(18)F-labeled-bioorthogonal liposomes for in vivo targeting.

DOI：
10.1021/bc400322h
发表时间：
2013-11-20
期刊：
BIOCONJUGATE CHEMISTRY
影响因子：
4.7
作者：
Emmetiere, Fabien;Irwin, Christopher;Viola-Villegas, Nerissa Therese;Longo, Valerie;Cheal, Sarah M.;Zanzonico, Pat;Pillarsetty, NagaVaraKishore;Weber, Wolfgang A.;Lewis, Jason S.;Reiner, Thomas
通讯作者：
Reiner, Thomas

Clinical Cerenkov luminescence imaging of (18)F-FDG.

DOI：
10.2967/jnumed.113.127266
发表时间：
2014-01
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
0
作者：
Thorek DL;Riedl CC;Grimm J
通讯作者：
Grimm J

The next generation of positron emission tomography radiopharmaceuticals in oncology.