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CORE--PEPTIDE AND OLIGONUCLEOTIDE LABORATORY

CORE--PEPTIDE AND OLIGONUCLEOTIDE LABORATORY
核心--肽及寡核苷酸实验室
批准号:
6564094
负责人:
HENRY T KEUTMANN
金额:
$14.33万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-12-01 至 2002-11-30

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中文摘要
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英文摘要
Description:(Taken directly from the application) The Peptide/ Oligonucleotide Core provides the Program Project with highly responsive, in-house resource for chemical-analytical and synthesis services and expertise through the following activities: (1) Preparation of synthetic peptides and analogs over a range of scales, followed by documentation of their homogeneity; (2) Performance of sequencing, mass spectroscopy, and amino acid compositional analyses of peptides and biosynthetic products; (3) Preparation of synthetic oligonucleotides for use as probes for screening, hybridization and site-directed mutagenesis; (4) Development and application of specialized chemical procedures such as cross linking, prosthetic group attachment and "customized" purification modalities; (5) Advice and consultation in synthesis and purification strategies and "hands-on" transfer of technologies to participating investigators.
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