ADAPTIVE OPTICS SCANNING LASER OPHTHALMOSCOPE

产品说明： 在健康的正常受试者中，视网膜的主要分辨率限制因素 眼底成像是由眼睛自身光学引起的像差。的 申请人是罗切斯特大学的一个研究小组的成员， 首次证明这些畸变可以用Shack测量， 哈特曼波前传感器和使用可变形反射镜消除的方法 称为自适应光学（AO）。申请人现已获得 NSF，休斯顿大学和Pharmacia和Upjohn开发了一种类似的 设备.该设备将被纳入扫描激光检眼镜 (SLO)而不是在罗切斯特中使用的更传统的眼底照相机设计。 这种SLO设计有可能大大减少散射的影响， 光，并进一步提高眼底成像的分辨率。

DESCRIPTION: In healthy normal subjects, the primary resolution limiting factors to retinal fundus imaging are the aberrations caused by the eyes' own optics. The applicant was among a team of investigators at the University of Rochester that first demonstrated that these aberrations could be measured with a Shack Hartman wavefront sensor and cancelled using a deformable mirror in a process called adaptive optics (AO). The applicant has now obtained funding from the NSF, University of Houston and Pharmacia and Upjohn to develop a similar device. This device would be incorporated into a scanning laser ophthalmoscope (SLO) rather than the more conventional fundus camera design used in Rochester. This SLO design has the potential to greatly decrease the effects of scattered light and further increase the resolution of fundus imaging.