CLINICAL TRIALS NETWORK, OHIO VALLEY NODE

临床试验网络，俄亥俄谷节点

• 批准号: 6664843
• 负责人: EUGENE C. SOMOZA
• 金额: $ 30万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6664843
• 关键词: biomedical equipment resource; clinical research; clinical trials; community health services; cooperative study; drug abuse; drug abuse therapy; human subject; human therapy evaluation; training

The Cincinnati Addiction Research Center (CinARC) proposes to form the Ohio Valley Node of the NIDA Clinical Trials Network (CTN) and to function as its Regional Research and Training Center (RRTC). The Ohio Valley Node would initially encompass the University of Cincinnati-based RRTC and six community-based treatment programs (CTPs) in Ohio, Indiana, Kentucky, and West Virginia. It would thus contribute a mid-western and Appalachian presence to the CTN, enhancing the network's geographical and cultural diversity. The goal of this proposal is to facilitate the CTN's evaluation and implementation of effective substance abuse treatments in community settings by operating a highly efficient and effective node that includes diverse treatment programs and patient populations. The Ohio Valley Node RRTC is primarily composed of the research team that has successfully conducted clinical trials for the Cincinnati NIDA Medication Development Research Unit (MDRU) since 1995. The RRTC team thus has extensive experience in conducting both single- and multi-site substance abuse trials in cooperation with NIDA and other NIDA-funded centers and has been recognized by NIDA for excellence in conducting clinical trials. The initial six CTPs of the Ohio Valley Node bring a rich variety of substance abuse services, treatment modalities, and patient populations to the CTN. Together, they treat almost 18,000 substance abuse patients per year from a population pool of 6.8 million persons. The CTPs have been highly involved in the development of this proposal and are committed to the goals of the CTN. The success of a CTN node is largely contingent upon establishing collaborative relationships among its RRTC and CTPs. The organizational and management plan of the Ohio Valley Node has been designed to enable the RRTC to provide the infrastructure, scientific leadership, and support functions necessary for successful operation while ensuring that the RRTC and CTPs are able to work collaboratively at a variety of levels. Parallel functional areas have been built into the RRTC, CTP, and node structures to facilitate communication between CTP and RRTC staff, to encourage the flow of experience-based insights from the CTPs to the RRTC, and to foster the transfer of technology from the RRTC to the CTPs.

辛辛那提成瘾研究中心（CinARC）提议组建俄亥俄州 NIDA临床试验网络（CTN）的谷节点，并作为其 区域研究和培训中心（RRTC）。俄亥俄州山谷节点将 最初包括总部位于伊利诺伊大学的RRTC和六个 俄亥俄州、印第安纳州、肯塔基州和西 弗吉尼亚因此，它将有助于中西部和阿巴拉契亚的存在， CTN，增强网络的地理和文化多样性。 本提案的目标是促进CTN的评估， 在社区环境中实施有效的药物滥用治疗， 运行一个高效和有效的节点，包括多样化的治疗 方案和患者群体。俄亥俄州山谷节点RRTC主要是 由成功进行临床试验的研究团队组成， 自1995年以来，为辛辛那提NIDA药物开发研究单位（MDRU）工作。 因此，RRTC团队在进行单次和 与NIDA和其他机构合作进行多地点药物滥用审判 NIDA资助的中心，并已被NIDA认可的卓越， 进行临床试验。俄亥俄州山谷节点的最初六个CTP带来了 丰富多样的药物滥用服务，治疗方式和患者 人口到CTN。他们总共治疗了近18,000名药物滥用者 每年从680万人的人口库中抽取患者。现金转拨方案 高度参与了该提案的制定，并致力于 CTN的目标。 CTN节点的成功很大程度上取决于建立协作 其RRTC和CTP之间的关系。组织和管理计划 俄亥俄州山谷节点的设计使RRTC能够提供 基础设施，科学领导和必要的支持功能， 成功运行，同时确保RRTC和CTP能够工作 在不同的层面上进行合作。平行功能区已 内置于RRTC、CTP和节点结构中，以促进通信 CTP和RRTC工作人员之间，以鼓励基于经验的见解的流动 从现金转拨方案到区域研究和技术中心，并促进从 RRTC到CTP。