CLINICAL TRIALS NETWORK, OHIO VALLEY NODE

辛辛那提成瘾研究中心(CinARC)提议成立俄亥俄州 NIDA临床试验网络(CTN)的山谷节点并作为ITS发挥作用 区域研究培训中心(RRTC)。俄亥俄山谷节点将 最初包括辛辛那提大学的RRTC和六个 俄亥俄州、印第安纳州、肯塔基州和西部的社区治疗计划(CTP) 弗吉尼亚。因此，它将有助于中西部和阿巴拉契亚地区的存在 CTN，加强该网络的地理和文化多样性。 这项提案的目标是促进CTN的评估和 在社区环境中实施有效的药物滥用治疗 运营高效和有效的节点，包括各种治疗 计划和患者群体。俄亥俄山谷节点RRTC主要是 由已成功进行临床试验的研究团队组成 自1995年以来在辛辛那提NIDA药物开发研究单位(MDRU)任职。 因此，RRTC团队在进行单项和 与NIDA和其他机构合作进行的多地点药物滥用试验 NIDA资助的中心，并因在 进行临床试验。俄亥俄山谷节点的最初六个CTP带来了 丰富的药物滥用服务、治疗方式和患者 将人口转移到CTN。他们总共治疗了近18,000种药物滥用 从680万人的人口池中，每年都有病人。CTP已经 高度参与该提案的制定，并致力于 CTN的目标。 CTN节点的成功在很大程度上取决于建立协作 其RRTC和CTP之间的关系。组织和管理计划 俄亥俄山谷节点的设计使RRTC能够提供 基础设施、科学领导和支持职能 成功运行，同时确保RRTC和CTP能够工作 在不同级别进行协作。平行功能区已经被 内置于RRTC、CTP和节点结构中，以促进通信 CTP和RRTC工作人员之间的沟通，以鼓励基于经验的见解的流动 从CTP到RRTC，并促进技术从 RRTC到CTP。

The Cincinnati Addiction Research Center (CinARC) proposes to form the Ohio Valley Node of the NIDA Clinical Trials Network (CTN) and to function as its Regional Research and Training Center (RRTC). The Ohio Valley Node would initially encompass the University of Cincinnati-based RRTC and six community-based treatment programs (CTPs) in Ohio, Indiana, Kentucky, and West Virginia. It would thus contribute a mid-western and Appalachian presence to the CTN, enhancing the network's geographical and cultural diversity. The goal of this proposal is to facilitate the CTN's evaluation and implementation of effective substance abuse treatments in community settings by operating a highly efficient and effective node that includes diverse treatment programs and patient populations. The Ohio Valley Node RRTC is primarily composed of the research team that has successfully conducted clinical trials for the Cincinnati NIDA Medication Development Research Unit (MDRU) since 1995. The RRTC team thus has extensive experience in conducting both single- and multi-site substance abuse trials in cooperation with NIDA and other NIDA-funded centers and has been recognized by NIDA for excellence in conducting clinical trials. The initial six CTPs of the Ohio Valley Node bring a rich variety of substance abuse services, treatment modalities, and patient populations to the CTN. Together, they treat almost 18,000 substance abuse patients per year from a population pool of 6.8 million persons. The CTPs have been highly involved in the development of this proposal and are committed to the goals of the CTN. The success of a CTN node is largely contingent upon establishing collaborative relationships among its RRTC and CTPs. The organizational and management plan of the Ohio Valley Node has been designed to enable the RRTC to provide the infrastructure, scientific leadership, and support functions necessary for successful operation while ensuring that the RRTC and CTPs are able to work collaboratively at a variety of levels. Parallel functional areas have been built into the RRTC, CTP, and node structures to facilitate communication between CTP and RRTC staff, to encourage the flow of experience-based insights from the CTPs to the RRTC, and to foster the transfer of technology from the RRTC to the CTPs.