Neural Control of Breathing and Cardiovascular Function

呼吸和心血管功能的神经控制

• 批准号: 6613286
• 负责人: MUSA A HAXHIU
• 金额: $ 12.24万
• 依托单位: HOWARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6613286
• 关键词: Neural; Control; Breathing; Cardiovascular; Function

DESCRIPTION (provided by applicant): This application seeks support to train scientific leaders in neural control of breathing and circulation. This program will support Ph.D. graduate students that will be selected based on undergraduate performance and their relevant research interest for their future careers. We have designed an integrated training program to prepare these future scientists to apply their skills to problems in pulmonary and cardiovascular functional disorders in relation to neuronal, behavioral and chemical control of breathing, and cardiovascular functions. Over the last 30 years the Ph.D. training program in Physiology and Biophysics, with particular emphasis on respiratory and cardiovascular control has graduated more than 30 trainees who are in research and teaching throughout the U.S. Under the leadership of Dr. M. A. Haxhiu as Program Director, Drs. C. Ovid Trouth and V. J. Massari as Program Co-Directors, and Dr. B. R. Coleman, Departmental Chairperson, we are committed to focus and intensify research on neural and hormonal control of breathing, airways, and circulation. This will be accomplished by, building on current research programs and maximizing our strengths in neuroscience, respiration and cardiovascular physiology, and expanding existing collaborations with established investigators in the Departments of Anatomy, Biochemistry, Pharmacology, Biology and Medicine. Our program faculties at Howard University and at the Collaborative Intensive Research Institutions are comprised of well established scientists, experienced trainers, and NIH-supported investigators who are working in interrelated areas of neural and hormonal control of breathing, airways and the cardiovascular system, all of which encompass both basic biologic and clinical components. Students may choose to focus their research project in control of breathing, airway functions, or the cardiovascular system. The availability of experienced mentorship and outstanding Collaborative Research Faculty in these interrelated fields and the strong interaction between these fields are the major components of this proposal. A "Neural and Hormonal Control of Breathing and Circulation" Seminar Series will serve as a nucleus for the trainees from both fields by providing a formal curriculum and an interactive "research in progress" component. Graduate students will have the opportunity to select courses in the basic sciences and will be trained in manuscript and grant preparation, in teaching and communication. In collaboration with designated Faculty at Case Western Reserve University, Johns Hopkins University, Mayo Medical School, University of Michigan, University of Wisconsin, and Yale University, we will offer vigorous, focused mentorship that will motivate our trainees to develop solid academic careers.

描述（由申请人提供）：本申请寻求支持培训呼吸和循环神经控制方面的科学领导者。 该计划将支持博士学位。将根据本科生的表现及其未来职业的相关研究兴趣来选择研究生。 我们设计了一个综合培训计划，帮助这些未来的科学家做好准备，将他们的技能应用于与呼吸的神经元、行为和化学控制以及心血管功能相关的肺和心血管功能障碍问题。 在过去的 30 年里，博士学位。生理学和生物物理学培训项目，特别强调呼吸和心血管控制，已毕业 30 多名学员，他们在美国各地从事研究和教学工作。 C. Ovid Trouth 和 V. J. Massari 作为项目联合主任，B. R. Coleman 博士作为系主任，我们致力于重点关注和加强对呼吸、气道和循环的神经和激素控制的研究。 这将通过以下方式实现：以当前的研究项目为基础，最大限度地发挥我们在神经科学、呼吸和心血管生理学方面的优势，并扩大与解剖学、生物化学、药理学、生物学和医学系的现有研究人员的现有合作。 我们在霍华德大学和合作强化研究机构的项目教师由知名科学家、经验丰富的培训师和 NIH 支持的研究人员组成，他们致力于呼吸、气道和心血管系统的神经和激素控制等相关领域，所有这些领域都涵盖基本的生物学和临床组成部分。 学生可以选择将他们的研究项目集中在呼吸控制、气道功能或心血管系统上。 在这些相互关联的领域中提供经验丰富的指导和杰出的合作研究人员以及这些领域之间的强有力的互动是该提案的主要组成部分。 “呼吸和循环的神经和激素控制”研讨会系列将通过提供正式课程和互动的“正在进行的研究”部分，作为这两个领域的学员的核心。 研究生将有机会选择基础科学课程，并接受手稿和资助准备、教学和交流方面的培训。 我们将与凯斯西储大学、约翰霍普金斯大学、梅奥医学院、密歇根大学、威斯康星大学和耶鲁大学的指定教师合作，提供积极、有针对性的指导，激励我们的学员发展扎实的学术生涯。