Neural Control of Breathing and Cardiovascular Function

描述（由申请人提供）：该申请寻求支持，以培训呼吸和循环神经控制方面的科学领导者。 该计划将支持博士。研究生将根据本科生的表现和他们未来职业的相关研究兴趣进行选择。 我们设计了一个综合培训计划，以准备这些未来的科学家将他们的技能应用于与呼吸的神经元，行为和化学控制以及心血管功能有关的肺和心血管功能障碍问题。 在过去的30年里，博士在生理学和生物物理学的培训计划，特别强调呼吸和心血管控制已毕业30多名学员谁是在研究和教学在美国各地。A. Haxhiu作为项目总监，Drs. C。奥维德特劳思和V.J.马萨里作为项目联合主任，B博士。R.科尔曼，系主任，我们致力于集中和加强对呼吸，气道和循环的神经和激素控制的研究。 这将通过建立在当前的研究计划基础上，最大限度地发挥我们在神经科学，呼吸和心血管生理学方面的优势，并扩大与解剖学，生物化学，药理学，生物学和医学部门的现有研究人员的合作来实现。 我们在霍华德大学和合作密集研究机构的计划学院由成熟的科学家，经验丰富的培训师和NIH支持的研究人员组成，他们在呼吸，气道和心血管系统的神经和激素控制的相关领域工作，所有这些都包括基本的生物和临床成分。 学生可以选择将他们的研究项目集中在呼吸控制，气道功能或心血管系统。 经验丰富的导师和优秀的合作研究教师在这些相互关联的领域和这些领域之间的强有力的互动的可用性是本提案的主要组成部分。 “呼吸和循环的神经和激素控制”系列研讨会将通过提供正式课程和互动的“正在进行的研究”部分，成为这两个领域学员的核心。 研究生将有机会选择基础科学课程，并将在手稿和赠款准备，教学和交流方面进行培训。 与凯斯西储大学、约翰霍普金斯大学、马约医学院、密歇根大学、威斯康星州大学和耶鲁大学的指定教师合作，我们将提供充满活力、专注的导师制，激励我们的学员发展坚实的学术事业。

DESCRIPTION (provided by applicant): This application seeks support to train scientific leaders in neural control of breathing and circulation. This program will support Ph.D. graduate students that will be selected based on undergraduate performance and their relevant research interest for their future careers. We have designed an integrated training program to prepare these future scientists to apply their skills to problems in pulmonary and cardiovascular functional disorders in relation to neuronal, behavioral and chemical control of breathing, and cardiovascular functions. Over the last 30 years the Ph.D. training program in Physiology and Biophysics, with particular emphasis on respiratory and cardiovascular control has graduated more than 30 trainees who are in research and teaching throughout the U.S. Under the leadership of Dr. M. A. Haxhiu as Program Director, Drs. C. Ovid Trouth and V. J. Massari as Program Co-Directors, and Dr. B. R. Coleman, Departmental Chairperson, we are committed to focus and intensify research on neural and hormonal control of breathing, airways, and circulation. This will be accomplished by, building on current research programs and maximizing our strengths in neuroscience, respiration and cardiovascular physiology, and expanding existing collaborations with established investigators in the Departments of Anatomy, Biochemistry, Pharmacology, Biology and Medicine. Our program faculties at Howard University and at the Collaborative Intensive Research Institutions are comprised of well established scientists, experienced trainers, and NIH-supported investigators who are working in interrelated areas of neural and hormonal control of breathing, airways and the cardiovascular system, all of which encompass both basic biologic and clinical components. Students may choose to focus their research project in control of breathing, airway functions, or the cardiovascular system. The availability of experienced mentorship and outstanding Collaborative Research Faculty in these interrelated fields and the strong interaction between these fields are the major components of this proposal. A "Neural and Hormonal Control of Breathing and Circulation" Seminar Series will serve as a nucleus for the trainees from both fields by providing a formal curriculum and an interactive "research in progress" component. Graduate students will have the opportunity to select courses in the basic sciences and will be trained in manuscript and grant preparation, in teaching and communication. In collaboration with designated Faculty at Case Western Reserve University, Johns Hopkins University, Mayo Medical School, University of Michigan, University of Wisconsin, and Yale University, we will offer vigorous, focused mentorship that will motivate our trainees to develop solid academic careers.