Training in Aging Research

描述(由申请人提供)：T32机构国家研究服务奖的新申请集中在老龄化研究方面强大且不断增长的研究计划，并包括一群精选的导师，他们在与老龄化相关的研究中拥有充足的科学努力。这些研究人员为爱因斯坦招募和培训新一代老年研究人员提供了杰出的基础。目前的新申请建立在早些时候T32拨款的基础上，最初是在1989年9月由阿尔伯特·爱因斯坦医学院(AECOM)授予的，并于1994年竞争性续签。我们选择了一个“两年的准备阶段”，旨在重新建立爱因斯坦的这个项目，提高它在我们机构内外的知名度，并实施新的招聘战略。在这方面，我们计划由申请的第三年开始，初步合共招收5名学员，并将学员总数由5名增至7名。另一方面，还应指出，自1999年以来，该机构加强了对老龄研究的承诺，这在一定程度上反映在国家老龄研究所(NIA)、NIH其他相关研究所、美国老龄研究联合会(FAR)和埃里森基金会增加的研究经费上。在这方面，在这段时间里，由NIA资助的爱因斯坦调查人员的数量从6人增加到14人，而这些奖项的年度直接成本增加了一倍多，达到约500万美元。最近老龄化研究的快速增长为爱因斯坦的老龄化研究培训提供了新的机会。 本申请所代表的研究学科包括：衰老的代谢综合征；衰老的脑功能和神经退行性疾病；心血管和衰老的细胞功能；免疫学和衰老；生长因子、细胞信号和癌症；以及衰老、更年期和妇女健康。我们的研究互动，以及对博士后和博士后受训者进行生物老年学原理的联合培训，使他们成为一个高度整合和有凝聚力的项目。通过正式的课程作业、参加研究研讨会和个人研究项目，受训者可以发展在老龄化研究中独立发展所需的技能。

DESCRIPTION (provided by applicant): This new application for a T32 Institutional National Research Service Award is centered on strong and growing research programs in aging research and includes a selective group of mentors with well-funded scientific endeavors in aging-related research. These investigators provide an outstanding foundation for the recruitment and training of a new generation of aging researchers at Einstein. The current new application builds on the foundation of an earlier T32 grant first awarded at the Albert Einstein College of Medicine (AECOM) in September 1989, and competitively renewed in 1994. We have elected to include a "two-year build-up" period designed to reinstitute this program at Einstein, promote its visibility within and outside our Institution, and implement novel recruitment strategies. In this regard, we plan to initially enroll a total of five trainees and to increase the total number of trainees from five to seven starting on the third year of this application. On the other hand, it should also be noted that since 1999, this Institution has enhanced its commitment to aging research as partly reflected by increasing research funding from the National Institute of Aging (NIA), other relevant NIH Institutes, the American Federation for Aging Research (AFAR), and the Ellison Foundation. In this regard, the number of Einstein investigators funded by the NIA rose from 6 to 14 during this period of time, while the annual direct cost of these awards more than doubled to approximately 5 million dollars. The recent rapid growth in aging research provides renewed opportunities for training in aging research at Einstein. The research disciplines represented in this application include metabolic syndromes of aging; aging brain functions and neurodegenerative diseases; cardiovascular and aging cellular functions; immunology and aging; growth factors, cell signaling, and cancer; and aging, menopause and women's health. Our research interactions and the joint training of pre-doctoral and post-doctoral trainees in principles of biogerontology lend themselves to a highly integrated and cohesive program. Through formal course work, participation in research seminars, and individual research projects, trainees can develop the skills necessary for independent careers in aging research.