Training in Aging Research

描述（由申请人提供）：T32机构国家研究服务奖的新申请集中在老龄化研究领域强大且不断发展的研究项目上，包括一组在老龄化相关研究领域有良好资助的科学努力的导师。这些研究人员为爱因斯坦招募和培训新一代老年研究人员提供了杰出的基础。目前的新申请建立在1989年9月阿尔伯特·爱因斯坦医学院（AECOM）首次授予的T32资助的基础上，并于1994年竞争性地更新。我们选择包括一个“两年的积累”期，旨在在爱因斯坦重新建立这个项目，提高其在我们机构内外的知名度，并实施新的招聘策略。在这方面，我们计划最初共招收五名学员，并在申请的第三年开始将学员总数从五人增加到七人。另一方面，也应该注意到，自1999年以来，本研究所加强了对老龄化研究的承诺，部分反映在国家老龄化研究所（NIA），其他相关NIH研究所，美国老龄化研究联合会（AFAR）和埃里森基金会增加了研究经费。在这方面，在此期间，由NIA资助的爱因斯坦研究人员的数量从6人增加到14人，而这些奖项的年度直接成本增加了一倍多，达到约500万美元。近年来老龄化研究的快速增长为爱因斯坦的老龄化研究提供了新的培训机会。

DESCRIPTION (provided by applicant): This new application for a T32 Institutional National Research Service Award is centered on strong and growing research programs in aging research and includes a selective group of mentors with well-funded scientific endeavors in aging-related research. These investigators provide an outstanding foundation for the recruitment and training of a new generation of aging researchers at Einstein. The current new application builds on the foundation of an earlier T32 grant first awarded at the Albert Einstein College of Medicine (AECOM) in September 1989, and competitively renewed in 1994. We have elected to include a "two-year build-up" period designed to reinstitute this program at Einstein, promote its visibility within and outside our Institution, and implement novel recruitment strategies. In this regard, we plan to initially enroll a total of five trainees and to increase the total number of trainees from five to seven starting on the third year of this application. On the other hand, it should also be noted that since 1999, this Institution has enhanced its commitment to aging research as partly reflected by increasing research funding from the National Institute of Aging (NIA), other relevant NIH Institutes, the American Federation for Aging Research (AFAR), and the Ellison Foundation. In this regard, the number of Einstein investigators funded by the NIA rose from 6 to 14 during this period of time, while the annual direct cost of these awards more than doubled to approximately 5 million dollars. The recent rapid growth in aging research provides renewed opportunities for training in aging research at Einstein. The research disciplines represented in this application include metabolic syndromes of aging; aging brain functions and neurodegenerative diseases; cardiovascular and aging cellular functions; immunology and aging; growth factors, cell signaling, and cancer; and aging, menopause and women's health. Our research interactions and the joint training of pre-doctoral and post-doctoral trainees in principles of biogerontology lend themselves to a highly integrated and cohesive program. Through formal course work, participation in research seminars, and individual research projects, trainees can develop the skills necessary for independent careers in aging research.