MBRS SCORE Program at Alabama A&M University

阿拉巴马州 A 的 MBRS SCORE 项目

• 批准号: 6804215
• 负责人: PURUSHOTTAM G KALE
• 金额: $ 4.39万
• 依托单位: ALABAMA AGRI AND MECH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6804215
• 关键词: clinical research; minority institution research support

DESCRIPTION (provided by applicant): Alabama A&M University, a HBCU institution, encourages and expects the faculty to develop research programs in order to increase the number of minorities professionally engaged in research. Accordingly, the university seeks federal research support, in this case, NIH, to develop faculty expertise to conduct competitive biomedical research. This application to NIH/SCORE program includes ten faculty from the departments of biology, chemistry, physics and food science, all interested in different biomedical areas. The subprojects are 1) Nonlinear optical study of blood rheology (Dr. Curley); 2) Optimization of the production of a fertile hypoallergenic peanut plant using A. tumefaciens (Dr. Dodo); 3) Rapid identification of fungi from indoor environment using metabolite profile and antigen detection techniques (Drs. Jones and Okafor); 4) Induction of mutations in Drosophila germ cells by gaseous radiation (Dr. Kale); 5) Computational studies of GP41 from HIV-1 (Dr. Kim); 6) Optical and electrical manipulation of microogranisms using optical trapping and electrical pulses (Drs. Kukhtarev); 7) Two-photon spectroscopy of novel anticancer agents (Dr. Sarkisov); 8) Inactivation of gram negative bacterial biofilm and planktonic cells (Dr. Tadros); 9) Anticarcinogenic potential of phytic acid, isositol and green tea in human colon carcinoma cells (Dr. Vergese). We expect that by the end of the proposed four year program, the faculty with pilot projects will be able to successfully compete for a regular SCORE project and faculty with regular SCORE project will be able to do so for the R01 application.

描述（由申请人提供）：阿拉巴马A&M大学是一所HBCU机构，鼓励并期望教师开发研究项目，以增加少数民族专业从事研究的人数。因此，该大学寻求联邦研究支持，在这种情况下，美国国立卫生研究院，以发展教师的专业知识，进行有竞争力的生物医学研究。本次NIH/SCORE项目的申请包括来自生物、化学、物理和食品科学系的10名教师，他们都对不同的生物医学领域感兴趣。子项目：1)血液流变学非线性光学研究（Curley博士）；2)利用a . tumefaciens （Dr. Dodo）优化可育低致敏性花生植株；3)利用代谢物谱和抗原检测技术快速鉴定室内环境中的真菌。琼斯和奥卡福)；4)气体辐射诱导果蝇生殖细胞突变（Dr. Kale）；5) HIV-1中GP41的计算研究（Dr. Kim）；6)利用光捕获和电脉冲对微生物进行光学和电学操作。Kukhtarev);7)新型抗癌药物的双光子光谱研究（Sarkisov博士）；8)革兰氏阴性细菌生物膜和浮游细胞的失活（Dr. Tadros）；植酸、异糖醇和绿茶对人类结肠癌细胞的抗癌作用（Vergese博士）。我们预计，在拟议的四年计划结束时，拥有试点项目的教师将能够成功竞争常规SCORE项目，而拥有常规SCORE项目的教师将能够竞争R01申请。