MBRS SCORE Program at Alabama A&M University

描述(由申请者提供)：HBCU旗下的阿拉巴马农工大学鼓励并期望教职员工开展研究项目，以增加从事专业研究的少数族裔人数。因此，该大学寻求联邦研究支持，在这种情况下，NIH，以发展教师专业知识，以进行有竞争力的生物医学研究。NIH/SCORE项目的申请包括来自生物、化学、物理和食品科学系的10名教员，他们都对不同的生物医学领域感兴趣。这些项目包括：1)血液流变学的非线性光学研究(柯利博士)；2)利用根癌农杆菌优化一种肥沃的低过敏性花生植株的生产(Dodo博士)；3)利用代谢物图谱和抗原检测技术快速鉴定室内环境中的真菌(Jones博士和Okafor博士)；4)气体辐射诱导果蝇生殖细胞的突变(Kale博士)；5)HIV-1中GP41的计算研究(Kim博士)；6)使用光学捕捉和电脉冲对微小颗粒进行光学和电学操作(Kukhtarev博士)；7)新型抗癌剂的双光子光谱(Sarksov博士)；8)革兰氏阴性细菌生物膜和浮游细胞的灭活(Tadros博士)；9)植酸、异山醇和绿茶在人类结肠癌细胞中的抗癌潜力(Vergese博士)。我们预计，在拟议的四年计划结束时，拥有试点项目的教员将能够成功竞争常规分数项目，而拥有常规分数项目的教师将能够成功竞争R01申请。

DESCRIPTION (provided by applicant): Alabama A&M University, a HBCU institution, encourages and expects the faculty to develop research programs in order to increase the number of minorities professionally engaged in research. Accordingly, the university seeks federal research support, in this case, NIH, to develop faculty expertise to conduct competitive biomedical research. This application to NIH/SCORE program includes ten faculty from the departments of biology, chemistry, physics and food science, all interested in different biomedical areas. The subprojects are 1) Nonlinear optical study of blood rheology (Dr. Curley); 2) Optimization of the production of a fertile hypoallergenic peanut plant using A. tumefaciens (Dr. Dodo); 3) Rapid identification of fungi from indoor environment using metabolite profile and antigen detection techniques (Drs. Jones and Okafor); 4) Induction of mutations in Drosophila germ cells by gaseous radiation (Dr. Kale); 5) Computational studies of GP41 from HIV-1 (Dr. Kim); 6) Optical and electrical manipulation of microogranisms using optical trapping and electrical pulses (Drs. Kukhtarev); 7) Two-photon spectroscopy of novel anticancer agents (Dr. Sarkisov); 8) Inactivation of gram negative bacterial biofilm and planktonic cells (Dr. Tadros); 9) Anticarcinogenic potential of phytic acid, isositol and green tea in human colon carcinoma cells (Dr. Vergese). We expect that by the end of the proposed four year program, the faculty with pilot projects will be able to successfully compete for a regular SCORE project and faculty with regular SCORE project will be able to do so for the R01 application.