MBRS SCORE Program at Alabama A&M University

描述（由申请人提供）：亚拉巴马A&M大学，HBCU机构，鼓励并期望教师开发研究计划，以增加少数民族专业从事研究的数量。因此，该大学寻求联邦研究支持，在这种情况下，国家卫生研究院，以发展教师的专业知识，进行有竞争力的生物医学研究。NIH/SCORE计划的申请包括来自生物学，化学，物理学和食品科学系的十名教师，他们都对不同的生物医学领域感兴趣。该子项目是：1）血液流变学的非线性光学研究（Curley博士）; 2）使用A.根癌农杆菌（Dr. Dodo）; 3）利用代谢物谱和抗原检测技术快速鉴定室内环境中的真菌（Jones和Okafor博士）; 4）通过气体辐射诱导果蝇生殖细胞突变（Kale博士）; 5）对HIV-1的GP 41进行计算研究（Kim博士）; 6）利用光捕获和电脉冲对微生物进行光学和电学操纵（Kukhtarev博士）; 7）新型抗癌剂的双光子光谱学（Sarkisov博士）; 8）革兰氏阴性细菌生物膜和嗜酸性细胞的灭活（Tadros博士）; 9）植酸、肌醇和绿色茶在人结肠癌细胞中的抗癌潜力（Vergese博士）。我们预计，到拟议的四年计划结束时，试点项目的教师将能够成功地竞争一个定期的SCORE项目和定期SCORE项目的教师将能够这样做的R 01应用程序。

DESCRIPTION (provided by applicant): Alabama A&M University, a HBCU institution, encourages and expects the faculty to develop research programs in order to increase the number of minorities professionally engaged in research. Accordingly, the university seeks federal research support, in this case, NIH, to develop faculty expertise to conduct competitive biomedical research. This application to NIH/SCORE program includes ten faculty from the departments of biology, chemistry, physics and food science, all interested in different biomedical areas. The subprojects are 1) Nonlinear optical study of blood rheology (Dr. Curley); 2) Optimization of the production of a fertile hypoallergenic peanut plant using A. tumefaciens (Dr. Dodo); 3) Rapid identification of fungi from indoor environment using metabolite profile and antigen detection techniques (Drs. Jones and Okafor); 4) Induction of mutations in Drosophila germ cells by gaseous radiation (Dr. Kale); 5) Computational studies of GP41 from HIV-1 (Dr. Kim); 6) Optical and electrical manipulation of microogranisms using optical trapping and electrical pulses (Drs. Kukhtarev); 7) Two-photon spectroscopy of novel anticancer agents (Dr. Sarkisov); 8) Inactivation of gram negative bacterial biofilm and planktonic cells (Dr. Tadros); 9) Anticarcinogenic potential of phytic acid, isositol and green tea in human colon carcinoma cells (Dr. Vergese). We expect that by the end of the proposed four year program, the faculty with pilot projects will be able to successfully compete for a regular SCORE project and faculty with regular SCORE project will be able to do so for the R01 application.