Transducer for indirect blood pressure& O2 saturation

间接血压传感器

• 批准号: 6725339
• 负责人: LESLIE A GEDDES
• 金额: $ 15万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6725339
• 关键词: artery; bioengineering /biomedical engineering; biomedical equipment development; blood pressure; clinical research; electrocardiography; human subject; laboratory rat; measurement; monitoring device; noninvasive diagnosis; oscillatory blood flow; pediatrics; pulmonary respiration; pulse pressure wave; respiratory oxygen; swine

DESCRIPTION (provided by applicant): It is proposed to complete development of a new type of noninvasive transducer that acquires systolic, mean and diastolic pressure, heart and respiratory rate and oxygen saturation to be used on premature and neonatal infants and small animals. The anesthetized weanling piglet tail will be used for direct comparisons. Human studies will employ the little finger and indirect wrist (radial artery) comparisons on subjects with very small little fingers. The number of births in the US in 1998 was 3,942,000 and among them the number of low birth weight infants (below 5 lb - 8oz) represents 7.8% of the whole population or 307,476 babies per year, and the number of very low birth-weight infants (below 3.3 Ibs.) is 45,000 per year. In veterinary medicine it is estimated that the market size for this device is around 20,400 units per year. Rats are used extensively in drug screening; this device is ideally suited for use in the rat tail. The outcome of this research will be a single instrument that indicates systolic, mean and diastolic pressure, pulse and respiratory rate and oxygen saturation, all derived from a single, member encompassing transducer. The neonatologist, the premature infant physician and the small-infant pediatrician have no single instrument that provides all of these vital signs.

描述(由申请人提供)： 建议完成一种新型的无创换能器的开发，该换能器可获得早产儿、新生儿和小动物的收缩压、平均压、舒张压、心率、呼吸频率和血氧饱和度。麻醉后的断奶仔猪尾巴将用于直接比对。人体研究将在小指非常小的受试者身上进行小指和间接手腕(桡动脉)的比较。 1998年，美国的出生人数为3,942,000人，其中低出生体重儿(5磅-8盎司以下)的人数占总人口的7.8%，即每年307,476名婴儿，以及极低出生体重儿(3.3磅以下)的人数。是每年45000人。在兽医方面，据估计，这种设备的市场规模约为每年20,400台。老鼠被广泛用于药物筛选；这种设备非常适合用于老鼠的尾巴。这项研究的结果将是一个单一的仪器，可以显示收缩压、平均压和舒张压、脉搏和呼吸频率以及血氧饱和度，所有这些都来自一个包含传感器的单一部件。新生儿科医生、早产儿内科医生和小儿科医生没有单一的仪器来提供所有这些生命体征。