BREATH-BY-BREATH METABOLIC MONITOR

这项研究的目的是开发和评估一个 氧耗计(新陈代谢监测仪)，可逐次呼吸 回应。这种独立的仪器是为麻醉而设计的 具有独特设计的小型换能器组件， 插入气管导管和麻醉机之间。这个 传感器组件包含低阻一次性和可消毒的 一种新的设计和快速响应的气体流量计 氧浓度探测器，也是一种新的设计，工作在 紫外线吸收原理。每一次呼吸的摄氧量是 每一次呼吸的体积(用气体测定仪测量)乘以 吸入氧气浓度和呼气氧气浓度的差异。新陈代谢 监护仪将显示心率、呼吸频率、潮气量和分钟数 体积，以及每呼吸和每分钟的摄氧量，这是 每一次吸气的分钟总和。 代谢监测器将在实验动物身上进行评估， 不同的麻醉条件。精选的试验也将在 气体麻醉下的人体受试者。

The objective of the research is to develop and evaluate an oxygen-consumption meter (metabolic monitor), capable of breath-by-breath response. The stand-alone instrument is designed for use in anesthesia monitoring and features a small transducer assembly of unique design that is inserted between the tracheal tube and the anesthesia machine. The transducer assembly contains a low-resistance disposable and sterilizable pneumotachograph of a new design and a rapidly responding oxygen-concentration detector, also of a new design, operating on the principle of ultraviolet absorption. The oxygen uptake per breath is the volume per breath (measured with the pneumotachograph) multiplied by the difference in inspired and expired oxygen concentration. The metabolic monitor will indicate heart rate, respiratory rate, tidal volume and minute volume, as well as the oxygen uptake per breath and per minute, which is the minute sum of the uptakes per breath. The metabolic monitor will be evaluated on experimental animals under a variety of anesthesia conditions. Selected trials will also be made on human subjects under gaseous anesthesia.