BREATH-BY-BREATH METABOLIC MONITOR

研究的目的是开发和评估一种 耗氧量计（代谢监测仪），能够逐呼吸 反应 独立仪器设计用于麻醉 监测和功能的独特设计的小型传感器组件， 插入气管导管和麻醉机之间。 的 传感器组件包含低电阻一次性和可消毒的 一种新设计的快速响应的呼吸速度计 氧气浓度检测器，也是一种新的设计，在 紫外线吸收原理 每次呼吸的氧摄取量是 每次呼吸量（用呼吸速度描记器测量）乘以 吸入和呼出的氧气浓度的差异。 代谢 监护仪将显示心率、呼吸率、潮气量和分钟 体积，以及每次呼吸和每分钟的氧摄取量， 每一次呼吸所吸收的微小总和。 代谢监测器将在实验动物中进行评价， 各种麻醉条件。 还将进行选定的试验， 在气体麻醉下的人类受试者。

The objective of the research is to develop and evaluate an oxygen-consumption meter (metabolic monitor), capable of breath-by-breath response. The stand-alone instrument is designed for use in anesthesia monitoring and features a small transducer assembly of unique design that is inserted between the tracheal tube and the anesthesia machine. The transducer assembly contains a low-resistance disposable and sterilizable pneumotachograph of a new design and a rapidly responding oxygen-concentration detector, also of a new design, operating on the principle of ultraviolet absorption. The oxygen uptake per breath is the volume per breath (measured with the pneumotachograph) multiplied by the difference in inspired and expired oxygen concentration. The metabolic monitor will indicate heart rate, respiratory rate, tidal volume and minute volume, as well as the oxygen uptake per breath and per minute, which is the minute sum of the uptakes per breath. The metabolic monitor will be evaluated on experimental animals under a variety of anesthesia conditions. Selected trials will also be made on human subjects under gaseous anesthesia.