Transducer for indirect blood pressure& O2 saturation

间接血压传感器

• 批准号: 6877053
• 负责人: LESLIE A GEDDES
• 金额: $ 15万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6877053
• 关键词: artery; bioengineering /biomedical engineering; biomedical equipment development; blood pressure; clinical research; electrocardiography; human subject; laboratory rat; measurement; monitoring device; noninvasive diagnosis; oscillatory blood flow; pediatrics; pulmonary respiration; pulse pressure wave; respiratory oxygen; swine

DESCRIPTION (provided by applicant): It is proposed to complete development of a new type of noninvasive transducer that acquires systolic, mean and diastolic pressure, heart and respiratory rate and oxygen saturation to be used on premature and neonatal infants and small animals. The anesthetized weanling piglet tail will be used for direct comparisons. Human studies will employ the little finger and indirect wrist (radial artery) comparisons on subjects with very small little fingers. The number of births in the US in 1998 was 3,942,000 and among them the number of low birth weight infants (below 5 lb - 8oz) represents 7.8% of the whole population or 307,476 babies per year, and the number of very low birth-weight infants (below 3.3 Ibs.) is 45,000 per year. In veterinary medicine it is estimated that the market size for this device is around 20,400 units per year. Rats are used extensively in drug screening; this device is ideally suited for use in the rat tail. The outcome of this research will be a single instrument that indicates systolic, mean and diastolic pressure, pulse and respiratory rate and oxygen saturation, all derived from a single, member encompassing transducer. The neonatologist, the premature infant physician and the small-infant pediatrician have no single instrument that provides all of these vital signs.

描述（由申请人提供）： 建议完成一种新型非侵入式传感器的开发，该传感器可采集收缩压、平均压和舒张压、心率和呼吸率以及氧饱和度，用于早产儿和新生儿以及小动物。 麻醉断奶仔猪尾部将用于直接比较。 人体研究将对小指非常小的受试者进行小指和间接手腕（桡动脉）比较。 1998年，美国的出生人数为3，942，000人，其中低出生体重婴儿（低于5磅-8盎司）的人数占总人口的7.8%，即每年307，476名婴儿，极低出生体重婴儿（低于3.3磅）的人数占总人口的7.8%。是每年四万五千人 在兽医领域，估计该器械的市场规模约为每年20，400台。 大鼠广泛用于药物筛选;该设备非常适合用于大鼠尾部。 这项研究的成果将是一个单一的仪器，表明收缩压，平均压和舒张压，脉搏和呼吸率和氧饱和度，所有来自一个单一的，成员包括传感器。 儿科医生、早产儿医生和小婴儿儿科医生没有一个单一的仪器可以提供所有这些生命体征。

项目成果

The natural biochemical changes during ventricular fibrillation with cardiopulmonary resuscitation and the onset of postdefibrillation pulseless electrical activity.

心肺复苏期间心室颤动和除颤后无脉电活动发生期间的自然生化变化。

• DOI: 10.1016/j.ajem.2006.01.030
• 发表时间: 2006
• 期刊: The American journal of emergency medicine.
• 作者: Geddes,LeslieA;Roeder,RebeccaA;Rundell,AnnE;Otlewski,MichaelP;Kemeny,AndreE;Lottes,AaronE
• 通讯作者: Lottes,AaronE