A strain respository for Dictyostelium discoideum

描述（由申请人提供）：群居变形虫盘齿骨是一种具有不断扩展的遗传技术的实验生物。除了它提供的实验优势外，这种变形虫还被用于解决许多生物学领域的问题，从细菌发病机制到趋化性和运动性，再到进化生物学，等等。该领域的工作人员正在生成大量菌株和其他有价值的工具，包括许多cDNA和突变文库。如果这些菌株和文库能够得到安全的储存和有效的分配，利用盘基骨菌的研究将会更加有效。因此，我们建议建立一个菌株库来保护、测试和分发该领域研究的原材料。该设施的馆长还将维护Dictyostelium参考数据库，目前已有7000多个参考数据库，并为希望利用Dictyostelium回答各种生物学问题的人提供其他帮助。我们设想了一个非常活跃的设施，为社区服务。

DESCRIPTION (provided by applicant):The social amoeba Dictyostelium is an experimental organism with an expanding repertoire of genetic techniques. In addition to the experimental advantages that it offers, this amoeba is being used to address questions in numerous areas of biology that range from bacterial pathogenesis to chemotaxis and motility, to evolutionary biology, among many others. The workers in the field are generating a large number of strains and other valuable tools, including many cDNA and mutant libraries. Research using Dictyostelium would be made more effective if these strains and libraries could be stored safely and distributed effectively. Therefore, we propose to establish a strain repository to secure, test, and distribute the raw material for research in this field. The curators of this facility would also maintain the database of Dictyostelium references, now numbering more than 7000, and provide other assistance to people who wish to exploit Dictyostelium to answer a variety of biological questions. We envisage a very active facility serving the community.