MASTER OF SCIENCE DEGREE IN CLINICAL INVESTIGATION

临床研究理学硕士学位

• 批准号: 6786557
• 负责人: MICHAEL J. LICHTENSTEIN
• 金额: $ 19.95万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6786557
• 关键词: Hispanic Americans; clinical research; curriculum; education evaluation /planning; ethics; experimental designs; health science research; minority health professional; postgraduate education; statistics /biometry; technical writing

In recent years, it has become obvious that there is a special need for investigators trained in clinical research. The biotechnology revolution has provided many possible avenues to improve 0ult, lives, but these advances require expertise in patient- oriented research for them to benefit mankind. We plan to use the resources we have in San Antonio to provide an innovative training program in clinical research to train young scientists, physicians, dentists, nurses and allied health professionals for successful careers in clinical investigation. We plan to do this through a new Master of Science Degree in Clinical Investigation (MSCI). The 'laboratory' for our trainees will be the General Clinical Research Center, which is an NIH-funded General Clinical Research Center located in one of our teaching hospitals. A special goal will be to increase the number of ethnically diverse students, particularly Mexican-Americans and other Hispanic groups, who will be trained in the conduct of clinical research. Once trained, graduates of this program will be expert in the design and conduct of patient-oriented research studies involving direct interactions between investigators and human subjects. The preceptors for this training program are faculty members with active programs in clinical research, molecular biology, protein chemistry and cell biology, and who have proven expertise in running successful research programs and in obtaining extramural grant support. Since MDs lack the formal didactic training characteristic of many Phi) programs, we have established an organized didactic program designed to prepare our trainees to function as future independent clinical researchers. Candidates enrolling in the MSCI program will complete a mentored research project over two years while participating in a highly integrated set of six didactic courses. The courses include: (a) Research Methodology (3 semesters); (b)Biostatistics (3 semesters); (c) Ethical Conduct of Research (I semester); (d) Integration of Molecular Biology into Clinical Research (l semester); (e) Data management, Quality Control, and Regulatory Issues (l semester); and (f) Scientific Writing (l semester). Our goal is to prepare investigators skilled in the conduct of outstanding clinical research in culturally diverse settings. MSCI program effectiveness will be ascertained by monitoring a cohesive set of five primary outcomes. These outcomes are: (a) the number of ethnically diverse trainees enrolled; (b) the number of enrolled students who attain their degrees; (c) the number of scientific peer-reviewed publications resulting from MSCI research projects; (d) the career paths chosen by the MSCI graduates; and (e) the success rate at which MSCI graduates compete for career development and research awards.

近年来，很明显，对临床研究人员的特殊需求。生物技术革命为改善老年人的生活提供了许多可能的途径，但这些进步需要以病人为导向的研究方面的专业知识，才能造福人类。我们计划利用我们在圣安东尼奥的资源，在临床研究方面提供一个创新的培训项目，培训年轻的科学家、医生、牙医、护士和相关的卫生专业人员，使他们在临床研究方面取得成功。我们计划通过一个新的临床研究理学硕士学位（MSCI）来实现这一目标。我们学员的“实验室”将是普通临床研究中心，这是美国国立卫生研究院资助的普通临床研究中心，位于我们的一所教学医院。一个特别的目标是增加不同种族学生的数量，特别是墨西哥裔美国人和其他西班牙裔群体，他们将接受临床研究方面的培训。经过培训后，该课程的毕业生将成为设计和实施以患者为导向的研究的专家，这些研究涉及研究者和人类受试者之间的直接互动。该培训计划的导师是在临床研究、分子生物学、蛋白质化学和细胞生物学方面有活跃项目的教师，他们在成功开展研究项目和获得校外资助支持方面具有成熟的专业知识。由于医学博士缺乏许多Phi项目的正式教学培训特征，我们建立了一个有组织的教学计划，旨在为我们的学员准备未来独立的临床研究人员。参加MSCI项目的候选人将在两年内完成一个有指导的研究项目，同时参加一套高度整合的六门教学课程。课程包括：(a)研究方法论（3个学期）；(b)生物统计学（3个学期）；(c)研究道德行为（一学期）；(d)分子生物学与临床研究的整合（1学期）；(e)数据管理、质量控制和管理问题（1学期）；(f)科学写作（1学期）。我们的目标是准备研究人员熟练地进行杰出的临床研究在多元文化的设置。MSCI计划的有效性将通过监测一组有凝聚力的五项主要结果来确定。这些结果是：(a)招收的不同种族的学员人数；（二）取得学位的在校学生人数；(c) MSCI研究项目产生的经同行评审的科学出版物的数量；(d) MSCI毕业生选择的职业道路；(e) MSCI毕业生竞争职业发展和研究奖项的成功率。