INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY (IPCS)

国际化学品安全方案(IPCS)成立于1980年，目的是以科学为基础应对全球对环境污染物对人类健康和环境构成的潜在危险的关切。IPCS是世界卫生组织(世卫组织)、国际劳工组织和联合国环境规划署的合作项目。IPCS(与本协定有关)的主要目标包括：1)协调国际和国家组织之间的化学品安全问题；2)编写以科学为基础的对化学品构成的风险的国际评估；3)就改进风险评估的科学基础所需的方法制定国际共识文件；以及4)处理新出现的全球环境健康问题。IPCS由世卫组织管理，并有少量核心工作人员驻扎在世卫组织日内瓦总部和北卡罗来纳州研究三角园区NIEHS园区的区域间研究股。IPCS通过来自33个国家70多个参与机构的国际科学专家组成的广泛网络完成大部分工作。NIEHS(校内和校外科学家)在IPCS的许多活动中发挥着重要的领导作用。这项建议的目的是为下列相互关联的全球环境问题提供及时、科学可靠的知识库和可信的评估：1)扰乱内分泌的化学品；2)环境与儿童健康；3)基因-环境相互作用；4)神经毒性；5)生殖毒理学；6)生物标志物；7)混合物；8)国际合作研究促进。这些目标的实施将产生各国将基本研究成果转化为全球公共卫生促进和预防实践所需的数据。

The International Programme on Chemical Safety (IPCS) was established in 1980 to provide a science-based response to global concerns about the potential dangers posed by environmental contaminants to human health and the environment. IPCS is a cooperative venture of the World Health Organization (WHO), the International Labour Organization and the United Nations Environment Programme. The major goals of IPCS (relevant to this Agreement) include 1) the coordination of chemical safety issues among international and national organizations; 2) the preparation of science-based international assessments of the risks posed by chemicals; 3) the development of international consensus documents on methodologies needed to improve the scientific basis for risk assessment; and 4) to address global emerging environmental health issues. IPCS is managed by WHO, and has a small core staff stationed at WHO Headquarters in Geneva and at the Interregional Research Unit (IRRU) on the NIEHS campus in Research Triangle Park, N.C. IPCS accomplishes much of its work through a broad network of international scientific experts from over 70 participating institutions in 33 countries. NIEHS (intramural and extramural scientists) play a significant leadership role for many IPCS activities. The aims of this proposal are to provide a timely, scientifically sound knowledge base and credible assessments for the following interrelated global environmental issues: 1) endocrine-disrupting chemicals; 2) environment and children's health; 3) gene-environment interactions; 4) neurotoxicity; 5) reproductive toxicology; 6) biomarkers; 7) mixtures; 8) international collaborative research promotion. Implementation of these aims will generate data needed for countries to translate basic research findings into global public health promotion and prevention practices.