Alcohol, risky behavior and AIDS in men

男性的酒精、危险行为和艾滋病

• 批准号: 6745702
• 负责人: STEPHEN A MAISTO
• 金额: $ 37.5万
• 依托单位: SYRACUSE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6745702
• 关键词: AIDS education /prevention; HIV infections; alcoholic beverage consumption; arousal; attitude; behavioral /social science research tag; bisexual; clinical research; clinical trials; condoms; educational resource design /development; expectancy; high risk behavior /lifestyle; homosexuals; human subject; interactive multimedia; male; neural information processing; neurotoxicology; questionnaires; safe sex /sex abstinence; sex behavior; social behavior; visual stimulus; young adult human (21-34)

(Revised Abstract) DESCRIPTION (provided by applicant): Men who engage in risky behavior have been most affected by the HIV/AIDS epidemic in the US. Furthermore, data suggest a recent upsurge in risk taking by such men, especially among individuals in the young adult age range. The long-term goal of this application is to advance understanding of alcohol intoxication as a determinant of risky behavior among young adult men on a given occasion. Understanding the influences of alcohol intoxication as part of a complex of variables is essential to enhancing the effectiveness of HIV prevention interventions. In this regard, HIV prevention interventions are not likely to be effective without knowledge of the determinants of risk behavior. This is especially critical among a population vulnerable to HIV that is experiencing a resurgence of new infections following a period of decline. The main short-term goals of this research are as follows: (1) To use formative research methods to (a) create two role-play scenarios that will be used as vehicles to measure risk exposure, negotiation skills, and intentions to engage in risky behavior and delivered by CD-ROM interactive video, and (b) select a sample of film clips that will be used in the proposed experiments; and (2) to conduct an experimental study of the effects of beverage administration and other factors, and has interaction as dependent variables relevant to the antecedents of safer behavior according to prominent theories of HIV prevention. The formative studies conducted to develop the role-plays will include 40 young adult men, and a total of 35 men will be recruited to help select the film clips. The experimental study will follow the conclusion of the formative studies. In the experiment, 184 young adult men will be assigned randomly to one of eight conditions formed by the combination of beverage administration (water control, placebo, low alcohol dose [BAC = .04%], or moderate alcohol dose [BAC = .08%]) and other factors. The primary dependent variables will be risk perception, risk exposure, negotiation skills, and intentions to engage in risky behavior.

（修订摘要）描述（由申请人提供）：从事风险行为的男性受到美国艾滋病毒/艾滋病流行的影响。此外，数据表明，最近在年轻人年龄段的人中，最近有这种男性冒险的风险增加。该应用的长期目标是提高对酒精中毒的理解，以决定在给定的情况下年轻人的风险行为的决定因素。将酒精中毒作为变量复合物的一部分的影响对于增强艾滋病毒预防干预措施的有效性至关重要。在这方面，如果不了解风险行为的决定因素，预防艾滋病毒的干预措施不太可能有效。这在容易受到艾滋病毒的人群中尤其至关重要，而艾滋病毒的损害正在经历一段时间后新感染的复兴。这项研究的主要短期目标如下：（1）使用形成性研究方法来（a）创建两个角色扮演场景，这些场景将用作衡量风险曝光，谈判技巧以及参与风险行为并通过CD-ROM交互式视频提供风险技巧的工具，以及（b）在拟议实验中使用的电影剪辑样本； （2）对饮料给药和其他因素的影响进行实验研究，并根据艾滋病毒预防的杰出理论与更安全行为的先例相关。开发角色扮演的形成性研究将包括40名年轻人，总共将招募35名男性以帮助选择胶片剪辑。实验研究将遵循形成性研究的结论。在实验中，将有184名年轻男性被随机分配到饮料给药（水控制，安慰剂，低酒精剂量[BAC = .04％]或中等酒精剂量[BAC = .08％]）和其他因素的八个条件之一。 主要的因变量将是风险感知，风险敞口，谈判技巧以及从事风险行为的意图。