Ovarian Cancer: Prevention and Its Recurrence

卵巢癌：预防及其复发

• 批准号: 6838458
• 负责人: FRANCESMARY MODUGNO
• 金额: $ 2万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6838458
• 关键词: cancer prevention; carcinogenesis; meeting /conference /symposium; neoplasm /cancer relapse /recurrence; ovary neoplasms

Following up on our very successful symosium on hormones and ovarian cancer prevention, we propose a series of symposia on prevention. The goal of this symposia series is to understand the genetic and biologic mechanisms involved in ovarian cancer and how these mechanisms can be exploited to devise innovative strategies for the prevention and detection of the disease and its recurrence. It will further address the impact of these modalities on the lives of women and their families. With advances in molecular biology and the emergence of new technologies (e.g., proteomics, genomics), we are gathering remarkable knowledge about the genetic and biologic basis of carcinogenesis. By directly facilitating our understanding of the disease process, this knowledge and technology is suggesting fruitful avenues of primary, secondary and tertiary. This series will bring together leaders in prevention, detection and treatment research in order to exchange their expertise, identify research avenues and form collaborations. The symposia series will be held every other year at the University of Pittsburgh Cancer Institute Herberman Conference Center. The general theme for the series is molecular targets and prevention; each symposium will have a specific theme: immune system, 2005; cell cycle 2006; pharmacogenetics, 2007; hormones 2008; and model systems 2009. The intended audience is basic, clinical and translational researchers in the areas of epidemiology, molecular biology, genetics, cell biology, endocrinology, pathology, gynecologic oncology, and high-throughput technologies, as well as public health researchers and consumer advocates. The specific goals of the workshop include: 1. to further understand the molecular, biologic and genetic mechanisms involved in ovarian cancer that can be targets for prevention; 2. to become familiar with emerging chemoprevention agents and early detection approaches aimed at molecular targets; 3. to learn about new highthroughput technologies; 4. to identify new areas of research based on the molecular mechanisms of the disease;All sessions include 2-3 scientific presentation followed by an open discussion by a leader in the field. A poster session will allow for participation by junior scientists and foster greater exchange of ideas. To date, there have been no other conferences specifically focused on the intersection of ovarian cancer, molecular targets and prevention (other than our 2002 symposium). This series represents a unique opportunity to bring together scientist, policy researchers and consumer advocates to advance the frontier of ovarian cancer research and public health.

继我们非常成功的关于激素和卵巢癌预防的研讨会之后，我们提议举办一系列关于预防的专题讨论会。该系列专题讨论会的目的是了解卵巢癌的遗传和生物学机制，以及如何利用这些机制来制定预防和检测疾病及其复发的创新策略。它将进一步讨论这些方式对妇女及其家庭生活的影响。随着分子生物学的进步和新技术（如蛋白质组学、基因组学）的出现，我们正在收集有关致癌的遗传和生物学基础的重要知识。通过直接促进我们对疾病过程的理解，这种知识和技术提供了丰富的初级、次级和