Ethnicity and Pregnancy Outcomes in New York City

纽约市的种族和怀孕结果

• 批准号: 7224351
• 负责人: David A Savitz
• 金额: $ 14.32万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7224351
• 关键词: African American; Asians; Hispanic Americans; Pacific Islander; United States; age difference; caucasian American; clinical research; developmental disease /disorder; education; gestational diabetes mellitus; human data; infant mortality; longitudinal human study; low birth weight infant human; marriage /marital status; outcomes research; preeclampsia; pregnancy disorder; pregnancy loss; pregnancy toxemia /hypertension; premature infant human; racial /ethnic difference; socioeconomics; statistics /biometry; women' s health

DESCRIPTION (provided by applicant): The major ethnic groups in the United States, African-Americans, Latinos, and Asians, show distinctive patterns of pregnancy outcome, including preterm birth, low birth weight, and infant mortality. Numerous reports have described this, but there has been little effort to extend these observations to address possible causal pathways underlying the patterns. In order to extend our understanding of the role of ethnicity and socioeconomic conditions on pregnancy outcome, we propose to analyze births in New York City over the period 1998-2002, a 5-year period straddling the 2000 Census, with over 500,000 births included in the final analysis. Through this combination of data sources, we will: describe ethnic patterns of pregnancy outcome, including preterm birth, growth restriction, and common pregnancy complications, characterize risk factors among women of varying ethnicity, including sociodemographic characteristics such as age, marital status, and education, and a number of medical conditions affecting the outcome of pregnancy. Measures of ethnicity at the individual level include race, Hispanic ethnicity, nativity, and ancestry, and we will be able to identify and analyze refined subgroups (e.g., Puerto Ricans, Asian Indians, Koreans) given the size and diversity of the New York City population. We will conduct a multi-level statistical analysis that takes into account both individual attributes from the birth certificate and neighborhood features from the US Census to examine their separate and joint effects, focusing on the influence of ethnicity, socioeconomic status, nativity, and concentration of ethnicity within Census Tracts. By elucidating the relationship between ethnicity and pregnancy outcome more fully, considering a broader range of ethnicities defined in greater detail, and integrating individual and community level socioeconomic influences, we will be better able to target groups in need of intervention as well as identify clues to etiology.

描述（由申请人提供）：美国的主要种族，非裔美国人、拉丁美洲人和亚洲人，在妊娠结局方面表现出独特的模式，包括早产、低出生体重和婴儿死亡率。许多报告都描述了这一点，但很少有人努力扩展这些观察结果，以解决这些模式背后可能的因果途径。为了扩展我们对种族和社会经济条件对怀孕结果的作用的理解，我们建议分析1998-2002年期间纽约市的出生情况，这是一个跨越2000年人口普查的5年期间，最终分析中包括了超过50万的出生情况。通过这种数据来源的组合，我们将：描述怀孕结果的种族模式，包括早产、生长受限和常见的妊娠并发症，描述不同种族妇女的风险因素，包括年龄、婚姻状况和教育等社会人口特征，以及影响怀孕结果的一些医疗条件。个人层面的种族衡量标准包括种族、西班牙裔、出生地和祖先，我们将能够识别和分析精细的子群体（例如，波多黎各人、亚洲印第安人、韩国人），考虑到纽约市人口的规模和多样性。我们将进行多层次的统计分析，同时考虑出生证明中的个人属性和美国人口普查中的社区特征，以检查它们单独和共同的影响，重点关注种族、社会经济地位、出生和人口普查区内种族集中的影响。通过更充分地阐明种族与妊娠结局之间的关系，更详细地考虑更广泛的种族定义，并整合个人和社区层面的社会经济影响，我们将能够更好地针对需要干预的群体，并识别病因线索。