GORDON RESEARCH CONFERENCE ON RADIATION ONCOLOGY

申请人的描述这是一个申请，以支持戈登研究会议上的“细胞和分子概念在放射肿瘤学”将在文图拉，加利福尼亚州举行的2001年1月28日至2月2日。 申请的资金将全部用于支持代表年轻教职员工的受邀演讲者的差旅费和注册费，以及部分支持在会议上展示海报的年轻调查人员。在我们对细胞对电离辐射反应的控制因素的理解方面，继续有着惊人的迅速进展。 这次会议的目的是审查和讨论有关辐射损害细胞的细胞和分子机制的最新数据。 这将通过从一系列专家中选出的特邀演讲者的演讲来实现，他们是各自研究领域的领导者，通过提供海报展示，以及通过全体与会者参与的全体讨论会来实现。 会议的一个特别目标是使年轻的研究人员与较资深的科学家在一个非正式的环境中聚集在一起，以促进广泛的互动，并鼓励自由交流意见。 预计约有100至130名与会者将出席会议，他们将从大学、研究机构以及政府和工业研究实验室中选出。 科学会议将确定令人兴奋的新信息正在出现的领域。 这些会议包括：1）辐射反应中的重组过程; 2）损伤识别途径; 3）氧化应激; 4）损伤反应途径; 5）辐射诱导的基因组不稳定性; 6）哺乳动物细胞死亡的机制; 7）新的辐射模型; 8）翻译模型;和9）旁观者效应。 还将为所有与会者举办四场海报会议，分享他们在会议适当领域的最新研究细节。 其中一些海报，特别是由年轻研究人员提出的海报，将被选为简短的平台介绍。 会议的一个首要目标是，所代表的各个领域的初级和高级科学家之间的交流将产生新的想法，并产生富有成效的合作。

APPLICANT'S DESCRIPTION This is an application for support for the Gordon Research Conference on "Cellular and Molecular Concepts in Radiation Oncology" to be held in Ventura, CA on January 28-February 2, 2001. The funds requested will be used entirely for the support of travel and registration fees for invited speakers who represent younger faculty members, as well as partial support for young investigators presenting posters at the meeting. There continues to be extraordinary rapid progress in our understanding of the factors governing the response of cells to ionizing radiation. The goal of this Conference is to examine and discuss recent data concerning the cellular and molecular mechanisms by which radiation damages cells. This will be achieved through presentations by invited speakers selected from a range of experts who are leaders in their research areas, by proffered poster presentations, and by plenary discussion sessions involving all attendees at the meeting. A particular objective of the Conference is to bring together young investigators with more senior scientists in an informal setting that will facilitate wide-ranging interactions and encourage a free exchange of ideas. Approximately 100 to 130 participants are expected to attend the meeting, chosen from universities, research institutes and governmental and industrial research laboratories. The scientific sessions will define areas in which exciting new information is emerging. These sessions include: 1) recombinational processes in radiation response; 2) damage recognition pathways; 3) oxidative stress; 4) damage response pathways; 5) radiation- induced genomic instability; 6) mechanisms of mammalian cell death; 7) new radiation models; 8) translational models; and 9) bystander effects. Four poster sessions will also be featured for all conference participants to share details of their latest research in areas appropriate to the Conference. Some of these posters, especially those presented by young investigators, will be selected for short platform presentations. An overriding goal of the Conference is that the cross-fertilization between junior and senior scientists in the various areas represented will generate new ideas and spawn productive collaborations.