TRANSLATIONAL RESEARCH AND SCIENCE EDUCATION

转化研究和科学教育

• 批准号: 6739301
• 负责人: TING-KAI K LI
• 金额: $ 19.52万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-01-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6739301
• 关键词: alcoholic beverage consumption; alcoholism /alcohol abuse; alcoholism /alcohol abuse education; behavioral /social science research tag; behavioral genetics; genetic susceptibility; health science research support

DESCRIPTION (provided by applicant): This component of the IARC competing renewal application qualifies the IARC for potential designation and funding as a Comprehensive Center (P60). The overall objective of the component is to advance alcohol research and its dissemination for the purpose of improving the treatment of alcohol-affected individuals and the prevention of alcohol-related problems. This will be accomplished through: (a) collaborative research partnerships with other institutions, especially minority and minority-serving institutions; (b) sponsoring and organizing the biennial scientific conference for pre- and post-doctoral fellows and young investigators; (c) continuing education opportunities to treatment professionals in clinical settings and to the community at large, especially those in the judiciary, administrative and legislative branches of State government; (d) the clinical teaching of the diagnosis and treatment of alcohol and drug abuse and dependence for (3rd year) medical students, and extension of the educational base to masters degree level students in the IU School of Social Work; (e) the Bench to Bench Program of Science Education in Alcohol Problems for Indiana Judges. These activities will draw upon the expertise of the IARC-affiliated faculty at Indiana and Purdue Universities that reflect the broadly-based research theme of the center's research programs: a) The genetic determinants of alcohol ingestive behavior and other responses to alcohol, b) The interplay of genetic, behavioral and social risk factors in the etiology of alcoholism, c) The neurobiological basis of alcohol addiction as manifested by craving, loss of control drinking, and relapse, which will serve as the basis for rational pharmacotherapeutic interventions, d) The intimate interaction of the pharmacokinetics of alcohol with its pharmacodynamic actions and how individual variability in both these domains influence susceptibility to problem and dependent drinking.

描述(由申请人提供)：IARC竞争续签申请的这一部分使IARC有资格被指定为综合中心并获得资金(第60页)。该构成部分的总体目标是促进酒精研究及其传播，目的是改善受酒精影响的个人的治疗和预防与酒精有关的问题。这将通过以下方式实现：(A)与其他机构，特别是少数群体和为少数群体服务的机构建立合作研究伙伴关系；(B)赞助和组织两年一次的博士后研究员和青年研究人员科学会议；(C)为临床环境中的治疗专业人员和广大社区，特别是州政府司法、行政和立法部门的专业人员提供继续教育机会；(D)为酒精和药物滥用和依赖的诊断和治疗提供临床教学(3年) (E)印第安纳州法官酒精问题科学教育方案。这些活动将利用印第安纳大学和普渡大学IARC附属教员的专业知识，这些专业知识反映了该中心研究计划的广泛研究主题：a)酒精摄取行为和对酒精的其他反应的遗传决定因素；b)遗传、行为和社会风险因素在酒精中毒病因中的相互作用；c)酒精成瘾的神经生物学基础，表现为渴望、饮酒失控和复发，这将成为合理药物治疗干预的基础；d)酒精的药代动力学及其药效作用的密切相互作用，以及这些领域的个体差异如何影响问题和依赖饮酒的易感性。