CORE--ANIMAL PRODUCTION

动物生产核心将提供选择性繁殖的P和NP （酒精偏好和非偏好）大鼠品系以及 选择性繁殖HAD和LAD（高酒精饮用和低酒精饮用）， 喝）老鼠的研究。 这些动物可用于 本机构ARC支持或附属的研究者 以及其他机构的合作和独立调查人员。 核心也将继续发展的P和NP近交系 菌株，开始近交的HAD和LAD系后，15代 选择和纠正出血异常，已发展中国家， NP大鼠通过回交P × NP后代到NP近交系。

The animal production core will provide selectively bred P and NP (alcohol-preferring and nonpreferring) lines of rats as well as the selectively bred HAD and LAD (high-alcohol-drinking and low-alcohol- drinking) rats for research. These animals are available to investigators supported by or affiliated with the ARC at this Institution and to collaborating and independent investigators at other Institutions. The Core will also continue the development of the P and NP inbred strains, begin inbreeding of the HAD and LAD lines after 15 generations of selection and correct the bleeding abnormality that has developed in the NP rats by backcrossing P x NP offspring to NP inbreds.