INDIVIDUAL, FAMILY AND SOCIETAL OUTCOMES OF INFERTILITY

不孕不育对个人、家庭和社会的影响

• 批准号: 6618137
• 负责人: NANCY E ADLER
• 金额: $ 157.85万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-21 至 2005-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6618137
• 关键词: assistive reproductive technique; fertility; psychological stressor; women's health

This Program Project proposal provides a comprehensive analysis of the psychological, social, economic, and medical outcomes of infertility diagnosis and treatment. The central theme is that couples and providers both face difficult decisions about the provision and use of reproductive technologies. Making the best choices requires comprehensive information about the likely costs and benefits, which may change during the course of treatment. Such information will permit better decision- making and outcomes for both patients and providers, and will identify the needs and opportunities for intervention during the trajectory of the diagnosis and treatment of infertility. The overall goals of the Program Project are to: (1) provide information on the costs and benefits of reproductive technology that will allow for better decision making and outcomes for both patients and providers; (2) identify the needs and opportunities for intervention during the trajectory of diagnosis and treatment of infertility, and (3) translate the findings into information that is useful for those considering the use of ARTs, clinicians, and policy markers. The aim of the project is to provide information that will be of use to infertile couples, providers of fertility services, insurers, health care purchasers and health care policy makers. The Program Project Director will be Nancy Adler, Ph.D., who will head the Steering Committee (SC). The SC will supervise and coordinate the activities of the Administrative Core; the Core for Data Collection, Management, and Analysis; the Advisory Board; and the component research projects. The component research projects will study decision- making processes of couples who are going through infertility treatment, the impact of these choices on couples' marital satisfaction and psychological well-being, the economic and social costs of these choices, and the pregnancy and birth outcomes that result from infertility and technological intervention. Data for three projects will be obtained by following a cohort of couples who seek an initial consultation of ART. A four project uses a different (and larger) database to determine the potential increased risk of adverse obstetric and pediatric outcomes in pregnancies resulting from treatment. The advantages of conducting together as a Program Project include the comprehensive analysis and multi-disciplinary perspective provided by the investigators, significant economies of scale as a result of using a single patient population for some and common methodologic and clinical support for all projects, and use of a common administrative structure. Most importantly, all projects draw upon existing relationships with infertility service providers in Northern California, without which a project as this could not be undertaken.

该计划项目提案对不孕症诊断和治疗的心理、社会、经济和医疗结果进行了全面分析。中心主题是，夫妇和提供者都面临着关于生殖技术的提供和使用的艰难决定。做出最佳选择需要有关可能的成本和收益的全面信息，这些信息可能在治疗过程中发生变化。这些信息将为患者和提供者提供更好的决策和结果，并将确定在不孕不育诊断和治疗过程中干预的需求和机会。该计划项目的总体目标是：(1) 提供有关生殖技术的成本和效益的信息，以便为患者和提供者提供更好的决策和结果； (2) 确定在不孕症诊断和治疗过程中干预的需求和机会，(3) 将研究结果转化为对考虑使用 ART 的人、临床医生和政策标记有用的信息。该项目的目的是提供对不孕夫妇、生育服务提供者、保险公司、医疗保健购买者和医疗保健政策制定者有用的信息。该计划的项目总监将是 Nancy Adler 博士，她将领导指导委员会 (SC)。 SC 将监督和协调行政核心的活动；数据收集、管理和分析的核心；顾问委员会；以及组成部分的研究项目。这些研究项目将研究正在接受不孕症治疗的夫妇的决策过程、这些选择对夫妇婚姻满意度和心理健康的影响、这些选择的经济和社会成本，以及不孕症和技术干预导致的怀孕和出生结果。三个项目的数据将通过跟踪一组寻求 ART 初步咨询的夫妇来获得。四个项目使用不同的（和更大的）数据库来确定因治疗而导致妊娠的不良产科和儿科结果的潜在增加风险。作为一个项目项目一起进行的优点包括研究人员提供的综合分析和多学科视角、由于使用单一患者群体为所有项目提供一些共同的方法和临床支持而产生的显着的规模经济，以及使用共同的管理结构。最重要的是，所有项目都利用了与北加州不孕不育服务提供商的现有关系，没有这些关系，项目就无法开展。

项目成果

Costs of infertility treatment: results from an 18-month prospective cohort study.

• DOI: 10.1016/j.fertnstert.2010.11.026
• 发表时间: 2011-03-01
• 期刊: FERTILITY AND STERILITY
• 影响因子: 6.7
• 作者: Katz, Patricia;Showstack, Jonathan;Smith, James F.;Nachtigall, Robert D.;Millstein, Susan G.;Wing, Holly;Eisenberg, Michael L.;Pasch, Lauri A.;Croughan, Mary S.;Adler, Nancy
• 通讯作者: Adler, Nancy

The Sexual Impact of Infertility Among Women Seeking Fertility Care.

• DOI: 10.1016/j.esxm.2016.04.001
• 发表时间: 2016-09
• 期刊: Sexual medicine
• 影响因子: 2.6
• 作者: Winkelman WD;Katz PP;Smith JF;Rowen TS;Infertility Outcomes Program Project Group
• 通讯作者: Infertility Outcomes Program Project Group

The use of complementary and alternative fertility treatment in couples seeking fertility care: data from a prospective cohort in the United States.

• DOI: 10.1016/j.fertnstert.2010.02.054
• 发表时间: 2010-05-01
• 期刊: Fertility and sterility
• 影响因子: 6.7
• 作者: Smith JF;Eisenberg ML;Millstein SG;Nachtigall RD;Shindel AW;Wing H;Cedars M;Pasch L;Katz PP;Infertility Outcomes Program Project Group
• 通讯作者: Infertility Outcomes Program Project Group

The measurement of childbearing motivation in couples considering the use of assisted reproductive technology.

• DOI: 10.1080/19485565.2008.9989129
• 发表时间: 2008-01-01
• 期刊: Biodemography and social biology
• 影响因子: 1.3
• 作者: Miller, Warren B;Millstein, Susan G;Pasta, David J
• 通讯作者: Pasta, David J

Time costs of fertility care: the hidden hardship of building a family.

• DOI: 10.1016/j.fertnstert.2013.01.145
• 发表时间: 2013-06
• 期刊: FERTILITY AND STERILITY
• 影响因子: 6.7
• 作者: Wu, Alex K.;Elliott, Peter;Katz, Patricia P.;Smith, James F.
• 通讯作者: Smith, James F.