Clinical/Translational Facilities for Innovative Oral Health Research at UIC

UIC创新口腔健康研究的临床/转化设施

• 批准号: 7899547
• 负责人: LYNDON F COOPER
• 金额: $ 991.56万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-18 至 2015-03-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7899547
• 关键词: Area; Cancer Biology; Clinical; Clinical Research; Collaborations; Core Facility; Dentistry; Equipment; Faculty; Funding; Future; Interdisciplinary Study; Laboratories; Mission; Occupations; Oral health; Recruitment Activity; Research; Research Personnel; Resources; Scheme; Scientist; Secure; Speed; Tissue Engineering; Training; Translational Research; Universities; Wound Healing; animal facility; college; design; improved; infrastructure development; innovation; programs; research facility; square foot; symposium

DESCRIPTION (provided by applicant): In order to fully realize its mission to become a leader in centers of innovative interdisciplinary research excellence and training of oral health scientists, the UIC College of Dentistry proposes to renovate 23,000 square feet of space into up-to-date, LEED-certified research space. The need for renovation is compelling. The College currently has no clinical research space, animal facilities that are filled to capacity, limited core facilities, and lab space that is so limited that faculty cannot grow their research programs. This project will add at least 9,000 square feet of new research space and renovate approximately 14,000 square feet of poorly configured 35 year old space. The scope of this project will include new Clinical Research Facilities, Animal Facilities, Core Facilities, and translational labs for funded investigators. The proposed project will allow the College to recruit and train basic, clinical, and translational scientists into the recently NIDCR-funded T32 (MOST Program); improve Core facility support for existing faculty; increase College faculty's ability to create collaborative projects within the University's newly funded Center for Clinical and Translational Science (CCTS); and speed up scientific progress within existing innovative research areas of Wound Healing, Cancer Biology and Tissue Engineering. The following specific aims have been developed: 1) Develop a new Clinical Research Facility in the College of Dentistry that will interact with and be a satellite of the CCTS; 2) Enlarge and optimize COD animal facilities to more than double current square footage; 3) Develop Core Facilities to enhance interaction among investigators and secure resources; and 4) Renovate laboratories to provide integrated functional space for current and future translational researchers who are developing the three research areas: Cancer Biology, Wound Healing and Tissue Engineering. In addition to green and sustainable principles, the design will increase opportunities for collaboration among faculty by creating new shared Core Facilities, new laboratories with shared equipment and conference rooms. The design scheme employs templates that have been used in the College to renovate previous lab space and therefore, we will move quickly from design to construction. The proposed renovations will help to complete the development of infrastructure in the College of Dentistry to bring these research foci to world class status and result in an estimated 20 new and 30 sustained jobs in laboratories and up to 60 new jobs in planning and construction.

描述(由申请者提供)：为了充分实现成为创新跨学科研究卓越中心和口腔健康科学家培训中心的领导者的使命，UIC牙科学院提议将23,000平方英尺的空间翻新为最新的、LEED认证的研究空间。翻新的需要是迫在眉睫的。该学院目前没有临床研究空间，动物设施已满，核心设施有限，实验室空间如此有限，以至于教职员工无法发展他们的研究项目。该项目将增加至少9,000平方英尺的新研究空间，并翻新约14,000平方英尺的配置不佳的35年旧空间。该项目的范围将包括新的临床研究设施、动物设施、核心设施和资助研究人员的翻译实验室。拟议的项目将使学院能够招聘和培训基础、临床和翻译科学家，进入最近由NIDCR资助的T32(MOST计划)；改善对现有教师的核心设施支持；提高学院教师在大学新资助的临床和翻译科学中心(CCTS)内创建合作项目的能力；并加快伤口愈合、癌症生物学和组织工程等现有创新研究领域的科学进展。制定了以下具体目标：1)在牙科学院开发一个新的临床研究设施，该设施将与CCTS互动并成为CCTS的卫星；2)扩大和优化COD动物设施，使其面积增加一倍以上；3)开发核心设施，以加强研究人员之间的互动和获得资源；以及4)翻新实验室，为正在发展三个研究领域的现有和未来的翻译研究人员提供综合的功能空间：癌症生物学、伤口愈合和组织工程。除了绿色和可持续的原则外，该设计还将通过创建新的共享核心设施、具有共享设备的新实验室和会议室来增加教职员工之间的合作机会。设计方案使用了学院已经使用的模板来翻新以前的实验室空间，因此，我们将快速从设计转移到施工。拟议的翻修将有助于完成牙科学院基础设施的发展，使这些研究重点达到世界级的地位，并在实验室产生约20个新的和30个持续的工作岗位，以及多达60个规划和建设方面的新工作岗位。