Clinical/Translational Facilities for Innovative Oral Health Research at UIC

UIC创新口腔健康研究的临床/转化设施

• 批准号: 7899547
• 负责人: LYNDON F COOPER
• 金额: $ 991.56万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-18 至 2015-03-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7899547
• 关键词: Area; Cancer Biology; Clinical; Clinical Research; Collaborations; Core Facility; Dentistry; Equipment; Faculty; Funding; Future; Interdisciplinary Study; Laboratories; Mission; Occupations; Oral health; Recruitment Activity; Research; Research Personnel; Resources; Scheme; Scientist; Secure; Speed; Tissue Engineering; Training; Translational Research; Universities; Wound Healing; animal facility; college; design; improved; infrastructure development; innovation; programs; research facility; square foot; symposium

DESCRIPTION (provided by applicant): In order to fully realize its mission to become a leader in centers of innovative interdisciplinary research excellence and training of oral health scientists, the UIC College of Dentistry proposes to renovate 23,000 square feet of space into up-to-date, LEED-certified research space. The need for renovation is compelling. The College currently has no clinical research space, animal facilities that are filled to capacity, limited core facilities, and lab space that is so limited that faculty cannot grow their research programs. This project will add at least 9,000 square feet of new research space and renovate approximately 14,000 square feet of poorly configured 35 year old space. The scope of this project will include new Clinical Research Facilities, Animal Facilities, Core Facilities, and translational labs for funded investigators. The proposed project will allow the College to recruit and train basic, clinical, and translational scientists into the recently NIDCR-funded T32 (MOST Program); improve Core facility support for existing faculty; increase College faculty's ability to create collaborative projects within the University's newly funded Center for Clinical and Translational Science (CCTS); and speed up scientific progress within existing innovative research areas of Wound Healing, Cancer Biology and Tissue Engineering. The following specific aims have been developed: 1) Develop a new Clinical Research Facility in the College of Dentistry that will interact with and be a satellite of the CCTS; 2) Enlarge and optimize COD animal facilities to more than double current square footage; 3) Develop Core Facilities to enhance interaction among investigators and secure resources; and 4) Renovate laboratories to provide integrated functional space for current and future translational researchers who are developing the three research areas: Cancer Biology, Wound Healing and Tissue Engineering. In addition to green and sustainable principles, the design will increase opportunities for collaboration among faculty by creating new shared Core Facilities, new laboratories with shared equipment and conference rooms. The design scheme employs templates that have been used in the College to renovate previous lab space and therefore, we will move quickly from design to construction. The proposed renovations will help to complete the development of infrastructure in the College of Dentistry to bring these research foci to world class status and result in an estimated 20 new and 30 sustained jobs in laboratories and up to 60 new jobs in planning and construction.

描述（由申请人提供）：为了充分实现其使命，成为创新的跨学科研究卓越和口腔健康科学家培训中心的领导者，牙科UIC学院建议将23,000平方英尺的空间改造成最新的LEED认证的研究空间。翻新的必要性是迫切的。该学院目前没有临床研究空间，动物设施已满，有限的核心设施和实验室空间是如此有限，教师不能发展他们的研究计划。该项目将增加至少9，000平方英尺的新研究空间，并翻新约14，000平方英尺的配置不良的35岁的空间。该项目的范围将包括新的临床研究设施、动物设施、核心设施以及供受资助研究人员使用的转化实验室。拟议的项目将允许学院招募和培训基础，临床和翻译科学家进入最近NIDCR资助的T32（MOST计划）;改善现有教师的核心设施支持;提高大学教师在大学新资助的临床和转化科学中心（CCTS）内创建合作项目的能力;加快伤口愈合、癌症生物学和组织工程等现有创新研究领域的科学进步。已经制定了以下具体目标：1）在牙科学院建立一个新的临床研究设施，该设施将与CCTS互动并成为CCTS的卫星; 2）扩大和优化COD动物设施，使其面积增加一倍以上; 3）发展核心设施，以加强研究人员之间的互动并确保资源;和4）改造实验室，为当前和未来正在开发三个研究领域的翻译研究人员提供综合功能空间：癌症生物学，伤口愈合和组织工程。除了绿色和可持续发展的原则，设计将通过创建新的共享核心设施，共享设备和会议室的新实验室，增加教师之间的合作机会。设计方案采用了已在学院使用的模板，以翻新以前的实验室空间，因此，我们将迅速从设计到施工。拟议的翻修将有助于完成牙科学院基础设施的发展，使这些研究重点达到世界一流的地位，并在实验室中创造约20个新的和30个持续的工作岗位，以及多达60个新的规划和建设工作岗位。